Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.58 |
| ▸ | JAK2 | O60674 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | HRH2 | P25021 | 1/20 | 0.57 |
| ▸ | CDK7 | P50613 | 1/20 | 0.57 |
| ▸ | CD69 | Q07108 | 1/20 | 0.57 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.57 |
| ▸ | MAP3K19 | Q56UN5 | 1/20 | 0.57 |
| ▸ | CDKL2 | Q92772 | 1/20 | 0.57 |
| ▸ | RIOK1 | Q9BRS2 | 1/20 | 0.57 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.57 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23275856 | 0.90 | BTK (0.59) | BTKJAK2CYP3A4HRH2CDK7 | |
| SCHEMBL28353387 | 0.86 | ABL1 (0.53) | BTKJAK2CYP3A4HRH2CDK7 | |
| SCHEMBL23275728 | 0.83 | JAK2 (0.68) | BTKJAK2CYP3A4HRH2CDK7 | |
| SCHEMBL23275831 | 0.82 | BTK (0.58) | BTKJAK2CYP3A4HRH2CDK7 | |
| SCHEMBL23281912 | 0.82 | ABL1 (0.49) | BTKJAK2CYP3A4HRH2CDK7 | |
| SCHEMBL31621209 | 0.81 | BTK (0.58) | BTKJAK2CYP3A4HRH2CDK7 | |
| SCHEMBL23281861 | 0.81 | BTK (0.58) | BTKJAK2CYP3A4HRH2CDK7 | |
| SCHEMBL23275874 | 0.80 | BTK (0.55) | BTKJAK2CYP3A4HRH2CDK7 | |
| SCHEMBL23275696 | 0.80 | CAMK2D (0.66) | BTKJAK2 | |
| SCHEMBL16793949 | 0.80 | BTK (0.75) | BTKJAK2CYP3A4HRH2CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021078023-A1 | SMALL MOLECULE COMPOUND | 嘉兴特科罗生物科技有限公司 | 2021-04-29 | — | — | WO | disclosed |
| CN-110627775-A | Small molecule compound | 嘉兴特科罗生物科技有限公司 | 2019-12-31 | — | — | CN | disclosed |