Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 4/20 | 0.46 |
| ▸ | MTOR | P42345 | 4/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.46 |
| ▸ | ATR | Q13535 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23283125 | 0.84 | NR3C1 (0.50) | PIK3CAMTORPIK3CGATRGPR119 | |
| SCHEMBL23283198 | 0.77 | NR3C1 (0.44) | PIK3CAMTORPIK3CGATRGPR119 | |
| SCHEMBL1061222 | 0.76 | GPR119 (0.44) | PIK3CAMTORPIK3CGATRGPR119 | |
| SCHEMBL1061142 | 0.75 | GPR119 (0.48) | PIK3CAMTORPIK3CGATRGPR119 | |
| SCHEMBL304441 | 0.74 | NR3C1 (0.50) | PIK3CAMTORPIK3CGATRGPR119 | |
| SCHEMBL9883047 | 0.74 | GPR119 (0.47) | PIK3CAMTORPIK3CGATRGPR119 | |
| SCHEMBL1060164 | 0.71 | GPR119 (0.45) | PIK3CAMTORPIK3CGATRGPR119 | |
| SCHEMBL1061732 | 0.71 | GPR119 (0.43) | PIK3CAMTORPIK3CGATRGPR119 | |
| SCHEMBL10060467 | 0.70 | GPR119 (0.42) | PIK3CAMTORPIK3CGATRGPR119 | |
| SCHEMBL1059433 | 0.70 | GPR119 (0.44) | PIK3CAMTORPIK3CGATRGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021080015-A1 | MODULATORS OF TREK (TWIK RELATED K+ CHANNELS) CHANNEL FUNCTION | ONO PHARMACEUTICAL CO., LTD. (JP) | 2021-04-29 | — | — | WO | disclosed |