SCHEMBL23283602

SCHEMBL23283602

COc1ccccc1CC(C)F

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.52
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.52
IDO1 P14902 2/20 0.50
TAAR1 Q96RJ0 1/20 0.50
CHRM2 P08172 1/20 0.48
CHRM1 P11229 1/20 0.48
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA4 P22748 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
ATM Q13315 1/20 0.46
HPGD P15428 1/20 0.45
HTT P42858 1/20 0.45
KMT2A Q03164 2/20 0.45
MEN1 O00255 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23886378 0.86 IDO1 (0.52) ALDH1A1GAAMAPTIDO1TAAR1
SCHEMBL878976 0.83 IDO1 (0.53) ALDH1A1GAAMAPTIDO1TAAR1
SCHEMBL14520623 0.80 IDO1 (0.50) ALDH1A1GAAMAPTIDO1TAAR1
SCHEMBL585112 0.80 IDO1 (0.50) ALDH1A1GAAMAPTIDO1TAAR1
SCHEMBL18473608 0.80 IDO1 (0.50) ALDH1A1GAAMAPTIDO1TAAR1
SCHEMBL30249073 0.80 KMT2A (0.64) IDO1TAAR1KMT2A
SCHEMBL5873472 0.80 IDO1 (0.50) ALDH1A1GAAMAPTIDO1TAAR1
SCHEMBL14655700 0.80 KMT2A (0.64) IDO1TAAR1KMT2A
SCHEMBL266563 0.80 KMT2A (0.64) IDO1TAAR1KMT2A
SCHEMBL29138530 0.79 IDO1 (0.46) ALDH1A1GAAMAPTIDO1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021080511-A1 METHODS OF BORYLATION AND USES THEREOF NATIONAL UNIVERSITY OF SINGAPORE (SG) 2021-04-29 WO disclosed