SCHEMBL29138530

SCHEMBL29138530

COc1ccccc1CC(F)CI

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.46
TAAR1 Q96RJ0 1/20 0.46
CHRM2 P08172 2/20 0.44
CHRM1 P11229 1/20 0.44
ALDH1A1 P00352 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
L3MBTL1 Q9Y468 2/20 0.42
ATM Q13315 1/20 0.42
CYP2D6 P10635 4/20 0.42
SLC6A2 P23975 4/20 0.42
SLC6A4 P31645 4/20 0.42
KCNH2 Q12809 4/20 0.42
SLC6A3 Q01959 3/20 0.42
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA4 P22748 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23886378 0.81 IDO1 (0.52) IDO1TAAR1CHRM2CHRM1ALDH1A1
SCHEMBL23283602 0.79 ALDH1A1 (0.52) IDO1TAAR1CHRM2CHRM1ALDH1A1
SCHEMBL4615134 0.78 IDO1 (0.57) IDO1TAAR1CHRM2CHRM1ALDH1A1
SCHEMBL878976 0.75 IDO1 (0.53) IDO1TAAR1CHRM2CHRM1ALDH1A1
SCHEMBL28805376 0.73 IDO1 (0.52) IDO1TAAR1CHRM2CHRM1ALDH1A1
SCHEMBL9480536 0.73 IDO1 (0.52) IDO1TAAR1CHRM2CHRM1ALDH1A1
SCHEMBL9638844 0.73 IDO1 (0.57) IDO1TAAR1CHRM2CHRM1ALDH1A1
SCHEMBL29735141 0.73 IDO1 (0.52) IDO1TAAR1CHRM2CHRM1ALDH1A1
SCHEMBL9480529 0.73 IDO1 (0.52) IDO1TAAR1CHRM2CHRM1ALDH1A1
SCHEMBL28334930 0.73 IDO1 (0.52) IDO1TAAR1CHRM2CHRM1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117069720-A 5-HT 2A Receptor agonist, preparation method and application thereof 上海翊石医药科技有限公司 2023-11-17 CN disclosed