Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25006980 | 0.85 | POLB (0.35) | POLBSMN1; SMN2GAAKMT2AESR2 | |
| SCHEMBL8354009 | 0.77 | SMN1; SMN2 (0.47) | POLBSMN1; SMN2KMT2AALDH1A1HPGD | |
| SCHEMBL10934685 | 0.76 | — | — | |
| SCHEMBL15965530 | 0.73 | MAPT (0.37) | POLBSMN1; SMN2GAAKMT2AESR2 | |
| SCHEMBL1398316 | 0.68 | ADAMTS5 (0.42) | POLBSMN1; SMN2KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL7993528 | 0.68 | — | — | |
| SCHEMBL507597 | 0.68 | — | — | |
| SCHEMBL16887640 | 0.65 | RAB9A (0.40) | SMN1; SMN2TDP1LMNA | |
| SCHEMBL3142222 | 0.63 | — | — | |
| SCHEMBL12883290 | 0.60 | SMN1; SMN2 (0.55) | POLBSMN1; SMN2GAAKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021078174-A1 | CHIRAL SULFUR OXIDE-CONTAINING ARYL FORMAMIDE COMPOUND AND SALT THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION, AND APPLICATION | 青岛清原化合物有限公司 | 2021-04-29 | — | — | WO | disclosed |