⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL866509 | 1.00 | — | — | |
| SCHEMBL455193 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL712887 | 0.98 | PPARG (0.36) | — | |
| SCHEMBL9480599 | 0.85 | SOAT1 (0.38) | — | |
| SCHEMBL9480609 | 0.85 | SOAT1 (0.38) | — | |
| SCHEMBL29957177 | 0.84 | S1PR1 (0.38) | — | |
| SCHEMBL865038 | 0.82 | GRIK1 (0.50) | — | |
| SCHEMBL866402 | 0.82 | GRIK1 (0.50) | — | |
| SCHEMBL11694674 | 0.79 | — | — | |
| SCHEMBL526332 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230391828-A1 | REGULATORS OF CELL DIVISION | TECHNISCHE UNIVERSITAT DRESDEN (DE) | 2023-12-07 | — | — | US | claimed |
| EP-4225780-A2 | REGULATORS OF CELL DIVISION | Technische Universität Dresden (DE) | 2023-08-16 | — | — | EP | claimed |
| WO-2022074072-A2 | REGULATORS OF CELL DIVISION | Technische Universität Dresden (DE) | 2022-04-14 | — | — | WO | claimed |
| EP-3981784-A1 | REGULATORS OF CELL DIVISION | Technische Universität Dresden (DE) | 2022-04-13 | — | — | EP | claimed |
| CN-113325110-A | Method for determining specific organic acid by tandem mass spectrometry | 浙江大学 | 2021-08-31 | — | — | CN | claimed |
| CN-113156096-A | Blood-based biomarkers for diagnosing coronary atherosclerotic disease | 全球基因集团有限责任公司 | 2021-07-23 | — | — | CN | claimed |
| CN-112585116-A | Synthesis of (2S, 3R, 4R) -4, 5-dihydroxyisoleucine and derivatives thereof | 海德堡医药研究有限责任公司 | 2021-03-30 | — | — | CN | claimed |
| WO-2018031531-A1 | ENGINEERED BACTERIA FOR NON-INVASIVE IMAGING AND THERAPEUTIC APPLICATIONS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-02-15 | — | — | WO | claimed |
| US-20150148524-A1 | AMINO ACID ANALOGUES AND METHODS FOR THEIR SYNTHESIS | UNIV MONASH (AU) | 2015-05-28 | — | — | US | claimed |
| EP-2870128-A1 | AMINO ACID ANALOGUES AND METHODS FOR THEIR SYNTHESIS | Monash University (AU) | 2015-05-13 | — | — | EP | claimed |
| WO-2011146974-A1 | METHODS FOR THE SYNTHESIS OF ALKYNE-CONTAINING DICARBA BRIDGES IN PEPTIDES | MONASH UNIVERSITY (AU) | 2011-12-01 | — | — | WO | claimed |
| WO-2011146972-A1 | METHODS FOR THE SYNTHESIS OF DICARBA BRIDGES IN PEPTIDES | MONASH UNIVERSITY (AU) | 2011-12-01 | — | — | WO | claimed |
| US-7723070-B2 | Adding an desired amino acid analog to a medium containing a host cell with a vector coding for aminoacyl-tRNA synthetase and a vector coding for the polypeptide of interest; and growing the cell to produce the modified polypeptide | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2010-05-25 | — | — | US | claimed |
| US-20080160609-A1 | Dihydrofolate reductase; site directed mutagenesis; point mutations; auxotroph host cells | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2008-07-03 | — | — | US | claimed |
| US-20070178554-A1 | Orthogonal Aminoacyl Synthetase-tRNA Pairs for Incorporating Unnatural Amino Acids Into Proteins | NEURION PHARMACEUTICALS, INC. | 2007-08-02 | — | — | US | claimed |
| US-7198915-B2 | Preparing modified/artificial polypeptides; mimetics | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-04-03 | — | — | US | claimed |
| US-20060014159-A1 | Methods of determining precise HERG interactions and designing compounds based on said interactions | NEURION PHARMACEUTICALS, INC. (US) | 2006-01-19 | — | — | US | claimed |
| US-20040058415-A1 | Preparing modified/artificial polypeptides; mimetics | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2004-03-25 | — | — | US | claimed |
| US-6586207-B2 | Host cell is a methionine auxotroph; methionine-tRNA synthetase overexpressed in presence of analogues and absence of methionine; protein is modified dihydrofolate reductase | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2003-07-01 | — | — | US | claimed |
| US-20020042097-A1 | Host cell is a methionine auxotroph; methionine-tRNA synthetase overexpressed in presence of analogues and absence of methionine; protein is modified dihydrofolate reductase | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2002-04-11 | — | — | US | claimed |