⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14896584 | 0.81 | S1PR1 (0.38) | — | |
| SCHEMBL232854 | 0.78 | — | — | |
| SCHEMBL8520637 | 0.78 | TSHR (0.42) | — | |
| SCHEMBL866509 | 0.78 | — | — | |
| SCHEMBL29956913 | 0.78 | — | — | |
| SCHEMBL467341 | 0.78 | — | — | |
| SCHEMBL455193 | 0.78 | — | — | |
| SCHEMBL4786114 | 0.78 | — | — | |
| SCHEMBL17667385 | 0.76 | TSHR (0.36) | — | |
| Hydrochloric Acid SCHEMBL712887 | 0.76 | PPARG (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120027677-A1 | Prion-specific peptoid reagents | NOVARTIS AG | 2012-02-02 | — | — | US | claimed |
| EP-2383281-A2 | Prion-specific peptoid reagents | Novartis AG (CH) | 2011-11-02 | — | — | EP | claimed |
| EP-0158556-B1 | PROCESS FOR THE PREPARATION OF HYDROXYALKYLAMINOACETIC ACIDS | SOCIETE FRANCAISE HOECHST Société anonyme dite: (FR) | 1987-07-01 | — | — | EP | claimed |
| US-4602106-A | Process for producing hydroxyalkylaminoacetic acids | SOCIETE FRANCAISE HOECHST (FR) | 1986-07-22 | — | — | US | claimed |
| EP-1931695-B1 | Prion-specific peptoid reagents | NOVARTIS AG (CH) | 2013-04-10 | — | — | EP | disclosed |
| US-20120027677-A1 | Prion-specific peptoid reagents | NOVARTIS AG | 2012-02-02 | — | — | US | disclosed |
| EP-2383281-A2 | Prion-specific peptoid reagents | Novartis AG (CH) | 2011-11-02 | — | — | EP | disclosed |
| US-20110189692-A1 | ASSAY FOR PATHOGENIC CONFORMERS | NOVARTIS AG | 2011-08-04 | — | — | US | disclosed |
| EP-2282753-A1 | ASSAY FOR PATHOGENIC CONFORMERS | Novartis AG (CH) | 2011-02-16 | — | — | EP | disclosed |
| US-7834144-B2 | Prion-specific peptoid reagents | NOVARTIS AG (CH) | 2010-11-16 | — | — | US | disclosed |
| WO-2009134942-A1 | ASSAY FOR PATHOGENIC CONFORMERS | NOVARTIS AG. (CH) | 2009-11-05 | — | — | WO | disclosed |
| EP-1931695-A1 | PRION-SPECIFIC PEPTOID REAGENTS | Novartis AG (CH) | 2008-06-18 | — | — | EP | disclosed |
| US-20070087972-A1 | Prion-specific peptoid reagents | NOVARTIS AG (CH) | 2007-04-19 | — | — | US | disclosed |
| WO-2007030804-A1 | PRION-SPECIFIC PEPTOID REAGENTS | NOVARTIS AG (CH) | 2007-03-15 | — | — | WO | disclosed |
| EP-0370145-A1 | Process for selectively removing hydrogen sulfide from a gas stream at high pressure | MOBIL OIL CORPORATION (US) | 1990-05-30 | — | — | EP | disclosed |
| EP-0248294-A2 | Detergent composition | Kao Corporation (JP) | 1987-12-09 | — | — | EP | disclosed |