Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CTH | P32929 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL232855 | 1.00 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2POLBEGLN1MAPT | |
| SCHEMBL820926 | 0.85 | — | — | |
| SCHEMBL11100545 | 0.85 | — | — | |
| SCHEMBL820925 | 0.85 | — | — | |
| SCHEMBL9480613 | 0.85 | CNR2 (0.50) | ALDH1A1SMN1; SMN2POLBEGLN1MAPT | |
| SCHEMBL23140079 | 0.81 | TGM2 (0.40) | ALDH1A1SMN1; SMN2POLBTGM2APEX1 | |
| SCHEMBL23140062 | 0.81 | TGM2 (0.40) | ALDH1A1SMN1; SMN2POLBTGM2APEX1 | |
| SCHEMBL2159350 | 0.80 | — | — | |
| SCHEMBL24703252 | 0.79 | TGM2 (0.39) | ALDH1A1SMN1; SMN2TGM2APEX1CNR2 | |
| SCHEMBL10810547 | 0.79 | TGM2 (0.39) | ALDH1A1SMN1; SMN2TGM2APEX1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022190030-A1 | A TOPICAL FORMULATION FOR THE TREATMENT OF SKIN DISEASES | AVACA PHARMA PRIVATE LIMITED (IN) | 2022-09-15 | — | — | WO | claimed |
| CN-113156096-A | Blood-based biomarkers for diagnosing coronary atherosclerotic disease | 全球基因集团有限责任公司 | 2021-07-23 | — | — | CN | claimed |
| CN-106537145-B | Small molecule biochemical profiling of individual subjects for disease diagnosis and health assessment | 麦特博隆股份有限公司 | 2020-08-25 | — | — | CN | claimed |
| CN-110525075-A | A kind of process of cigarette 3D raster print product | HUBEI CHINA TOBACCO IND CO LTD | 2019-12-03 | — | — | CN | claimed |
| CN-109384881-A | A kind of method that cationic polymer preparation subtracts jelly | 湖北工业大学 | 2019-02-26 | — | — | CN | claimed |
| CN-109134780-A | A kind of hard and soft cabinet-type polycarboxylate water-reducer of main chain and preparation method | 湖北工业大学 | 2019-01-04 | — | — | CN | claimed |
| CN-109053967-A | A kind of stepwise hydrolysis release type polycarboxylic acid slump retaining agent and preparation method | 湖北工业大学 | 2018-12-21 | — | — | CN | claimed |
| CN-109053966-A | 2200 molecular weight polyether polycarboxylate water-reducers of one kind and preparation method | 湖北工业大学 | 2018-12-21 | — | — | CN | claimed |
| CN-108911561-A | 2200 molecular weight polyether polycarboxylic acid slump retaining agents of one kind and preparation method | 湖北工业大学 | 2018-11-30 | — | — | CN | claimed |
| CN-108585594-A | A kind of high and easy retentivity polycarboxylate water-reducer of 1800 molecular weight polyethers and preparation method | 湖北工业大学 | 2018-09-28 | — | — | CN | claimed |
| WO-2011051813-A1 | COMPOSITIONS AND METHODS FOR TREATING DERMATOLOGICAL CONDITIONS | PAUL HARBHAJAN S (US) | 2011-05-05 | — | — | WO | claimed |
| US-20110098229-A1 | COMPOSITIONS AND METHODS FOR TREATING DERMATOLOGICAL CONDITIONS | BIOMED RESEARCH & TECHNOLOGIES, INC. | 2011-04-28 | — | — | US | claimed |
| EP-1098630-A2 | COMPOSITION FOR ENHANCING EPIDERMAL LIPID PRODUCTION | Biomed Research and Technologies, Inc. (US) | 2001-05-16 | — | — | EP | claimed |
| US-6149924-A | FOR TOPICAL APPLICATION | BIOMED RESEARCH & TECHNOLOGIES, INC. (US) | 2000-11-21 | — | — | US | claimed |
| WO-2000004870-A2 | COMPOSITION FOR ENHANCING EPIDERMAL LIPID PRODUCTION | BIOMED RESEARCH AND TECHNOLOGIES, INC. (US) | 2000-02-03 | — | — | WO | claimed |
| US-5773522-A | PRODRUGS FOR TREATMENT OF TUMORS | PHARMACIA S.P.A. (IT) | 1998-06-30 | — | — | US | claimed |
| US-5415864-A | Colonic-targeted oral drug-dosage forms based on crosslinked hydrogels containing azobonds and exhibiting PH-dependent swelling | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 1995-05-16 | — | — | US | claimed |
| EP-0544671-A4 | COLONIC-TARGETED ORAL DRUG-DOSAGE FORMS BASED ON CROSSLINKED HYDROGELS CONTAINING AZOBONDS AND EXHIBITING PH-DEPENDENT SWELLING | — | 1993-09-15 | — | — | EP | claimed |
| EP-0544671-A1 | COLONIC-TARGETED ORAL DRUG-DOSAGE FORMS BASED ON CROSSLINKED HYDROGELS CONTAINING AZOBONDS AND EXHIBITING pH-DEPENDENT SWELLING | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 1993-06-09 | — | — | EP | claimed |
| WO-1991016057-A1 | COLONIC-TARGETED ORAL DRUG-DOSAGE FORMS BASED ON CROSSLINKED HYDROGELS CONTAINING AZOBONDS AND EXHIBITING pH-DEPENDENT SWELLING | UNIVERSITY OF UTAH (US) | 1991-10-31 | — | — | WO | claimed |