SCHEMBL232865

SCHEMBL232865

CCO[Si](C)(CCC(C)N)OCC

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.37
TP53 P04637 1/20 0.30
GABRP O00591 2/20 0.30
GABRD O14764 2/20 0.30
GABRA1 P14867 2/20 0.30
GABRB1 P18505 2/20 0.30
GABRG2 P18507 2/20 0.30
GABRB3 P28472 2/20 0.30
GABRA5 P31644 2/20 0.30
GABRA3 P34903 2/20 0.30
GABRA2 P47869 2/20 0.30
GABRB2 P47870 2/20 0.30
GABRA4 P48169 2/20 0.30
GABRE P78334 2/20 0.30
GABRA6 Q16445 2/20 0.30
GABRG1 Q8N1C3 2/20 0.30
GABRG3 Q99928 2/20 0.30
GABRQ Q9UN88 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21056135 0.83
SCHEMBL27791955 0.82
SCHEMBL28071786 0.82
SCHEMBL1843724 0.81
SCHEMBL2556471 0.81 OPRM1 (0.37) OPRM1TP53GABRPGABRDGABRA1
SCHEMBL11186806 0.80
SCHEMBL1606773 0.80
SCHEMBL375455 0.79
SCHEMBL732360 0.79
SCHEMBL587426 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 467 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103172830-A Method for modifying acrylic ester by using organic silicon UNIV HUAINAN UNION 2013-06-26 CN claimed
US-7541123-B2 Imaging member XEROX CORPORATION (US) 2009-06-02 US claimed
US-20060284194-A1 Imaging member XEROX CORPORATION 2006-12-21 US claimed
CN-1478801-A Method of modifying acrylate using organic silicone 中国科学院广州化学研究所 2004-03-03 CN claimed
US-12570899-B2 Bright silver based quaternary nanostructures SHOEI CHEMICAL INC. (JP) 2026-03-10 US disclosed
US-20240263069-A1 BRIGHT SILVER BASED QUATERNARY NANOSTRUCTURES SHOEI CHEMICAL INC. (JP) 2024-08-08 US disclosed
US-11970646-B2 Bright silver based quaternary nanostructures SHOEI CHEMICAL INC. (JP) 2024-04-30 US disclosed
EP-3816247-B1 CURING MIXTURE EVONIK OPERATIONS GMBH (DE) 2022-12-07 EP disclosed
US-20220228057-A1 BRIGHT SILVER BASED QUATERNARY NANOSTRUCTURES NANOSYS, INC. (US) 2022-07-21 US disclosed
US-11254819-B2 Curing agent mixture EVONIK OPERATIONS GMBH (DE) 2022-02-22 US disclosed
EP-2994495-B2 CROSSLINKING OF IPMS ADDUCTS AND AMINOSILANES EVONIK OPERATIONS GMBH (DE) 2021-09-22 EP disclosed
EP-3816247-A1 CURING MIXTURE Evonik Operations GmbH (DE) 2021-05-05 EP disclosed
EP-0289216-A2 Electrophotographic imaging member XEROX CORPORATION (US) 1988-11-02 EP disclosed
US-4780385-A GREATER RESISTANCE TO FORMATION OF CHARGE DEFICIENT SPOTS XEROX CORPORATION (US) 1988-10-25 US disclosed
EP-0149914-B1 OVERCOATED ELECTROPHOTOGRAPHIC IMAGING MEMBER XEROX CORPORATION (US) 1988-08-10 EP disclosed
US-4588667-A Electrophotographic imaging member and process comprising sputtering titanium on substrate XEROX CORPORATION (US) 1986-05-13 US disclosed
EP-0161933-A2 Electrophotographic imaging XEROX CORPORATION (US) 1985-11-21 EP disclosed
EP-0149914-A1 Overcoated electrophotographic imaging member XEROX CORPORATION (US) 1985-07-31 EP disclosed
US-4515882-A CHARGE TRANSFER COMPOUNDS AND CHARGE INJECTION ENABLING PARTICLES XEROX CORPORATION (US) 1985-05-07 US disclosed
US-4291110-A ELECTROGRAPHY XEROX CORPORATION (US) 1981-09-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12570899-B2 Bright silver based quaternary nanostructures LGALS3, ANXA3, ATXN2L OPRM1 2012/4885TP53 286/4885GABRP 3550/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.