Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 5/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | GLP1R | P43220 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29559474 | 0.89 | TLR7 (0.48) | ACSS2PTGER4TLR7KDM4EALDH1A1 | |
| SCHEMBL20280108 | 0.89 | TLR7 (0.48) | ACSS2PTGER4TLR7KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL20266404 | 0.88 | TLR7 (0.47) | ACSS2PTGER4TLR7KDM4EALDH1A1 | |
| SCHEMBL29993371 | 0.82 | PKM (0.47) | ACSS2PTGER4ALDH1A1PKMHTT | |
| SCHEMBL23287370 | 0.82 | ACSS2 (0.43) | ACSS2PTGER4TLR7KDM4EALDH1A1 | |
| SCHEMBL22009843 | 0.82 | GLP1R (0.51) | ACSS2KDM4EALDH1A1GLAGAA | |
| SCHEMBL30676073 | 0.82 | GLP1R (0.51) | ACSS2KDM4EALDH1A1GLAGAA | |
| SCHEMBL23287296 | 0.81 | KDM4E (0.41) | ACSS2PTGER4TLR7KDM4EALDH1A1 | |
| SCHEMBL23287097 | 0.81 | CNR2 (0.42) | ACSS2PTGER4TLR7KDM4EALDH1A1 | |
| SCHEMBL23273512 | 0.81 | KDM4E (0.41) | ACSS2PTGER4TLR7KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021081207-A1 | GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2021-04-29 | — | — | WO | disclosed |