Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KLK7 | P49862 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23288564 | 0.89 | KMT2A (0.47) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL23288524 | 0.84 | FFAR1 (0.41) | KMT2ANPC1RAB9AALDH1A1MAPT | |
| SCHEMBL23288502 | 0.75 | KMT2A (0.43) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL23288563 | 0.73 | ALDH1A1 (0.42) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL23288559 | 0.70 | FFAR1 (0.41) | KMT2AMEN1ALDH1A1MMP2MMP9 | |
| SCHEMBL23288525 | 0.69 | ALDH1A1 (0.46) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL23288562 | 0.69 | ALDH1A1 (0.46) | KMT2AMEN1NPC1RAB9APOLB | |
| SCHEMBL23288566 | 0.69 | FFAR1 (0.41) | KMT2AALDH1A1MMP2MMP9MMP12 | |
| SCHEMBL7099035 | 0.68 | MEN1 (0.78) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10689366 | 0.65 | KLK7 (0.53) | KMT2AMEN1ALDH1A1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021081315-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CRYPTOSPORIDIOSIS | THE BROAD INSTITUTE, INC. (US) | 2021-04-29 | — | — | WO | disclosed |