Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.34 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.34 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.34 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23288560 | 0.89 | ALDH1A1 (0.36) | FFAR1ALDH1A1KMT2APTGESALOX5 | |
| SCHEMBL23288559 | 0.88 | FFAR1 (0.41) | FFAR1ALDH1A1KMT2AMMP2MMP9 | |
| SCHEMBL23288561 | 0.88 | FFAR1 (0.43) | FFAR1ALDH1A1KMT2AMMP2MMP9 | |
| SCHEMBL23288539 | 0.85 | ALOX5 (0.42) | FFAR1ALDH1A1KMT2APTGESFFAR4 | |
| SCHEMBL23288553 | 0.81 | FFAR1 (0.41) | FFAR1ALDH1A1KMT2APTGESACACB | |
| SCHEMBL23288524 | 0.81 | FFAR1 (0.41) | FFAR1ALDH1A1KMT2AMMP2MMP9 | |
| SCHEMBL23288508 | 0.80 | ALDH1A1 (0.41) | FFAR1ALDH1A1KMT2AMMP2FFAR4 | |
| SCHEMBL23288517 | 0.78 | FFAR1 (0.43) | FFAR1ALDH1A1KMT2APTGESACACB | |
| SCHEMBL23288564 | 0.72 | KMT2A (0.47) | ALDH1A1KMT2AMMP2MMP9MMP12 | |
| SCHEMBL23288565 | 0.70 | ALOX5 (0.45) | ALDH1A1KMT2AMMP2MMP3ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021081315-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF CRYPTOSPORIDIOSIS | THE BROAD INSTITUTE, INC. (US) | 2021-04-29 | — | — | WO | disclosed |