Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24575865 | 0.79 | CA1 (0.48) | CA12CA1CA2CA9EPHX1 | |
| SCHEMBL26908303 | 0.77 | — | — | |
| SCHEMBL390230 | 0.76 | MEN1 (0.32) | — | |
| SCHEMBL8012777 | 0.75 | MEN1 (0.31) | — | |
| SCHEMBL219412 | 0.73 | ALDH1A1 (0.40) | — | |
| SCHEMBL28647211 | 0.72 | MEN1 (0.38) | EPHX1 | |
| SCHEMBL2330280 | 0.71 | OSBP (0.32) | — | |
| SCHEMBL64929 | 0.71 | MEN1 (0.37) | — | |
| SCHEMBL1666983 | 0.71 | CA1 (0.44) | CA12CA1CA2CA9EPHX1 | |
| SCHEMBL7173632 | 0.70 | MEN1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786913-B1 | METHOD FOR THE PRODUCTION OF DIARYLCYCLOALKYL DERIVATIVES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-08-17 | — | — | EP | disclosed |
| US-7803950-B2 | Method for the production of diarylcycloalkyl derivatives | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2010-09-28 | — | — | US | disclosed |
| US-20080051583-A1 | NOVEL INTERMEDIATE COMPOUNDS USEFUL IN THE PRODUCTION OF DIARYLCYCLOALKYL DERIVATIVES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-02-28 | — | — | US | disclosed |
| US-20070197614-A1 | METHOD FOR THE PRODUCTION OF DIARYLCYCLOALKYL DERIVATIVES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-08-23 | — | — | US | disclosed |
| EP-1786913-A2 | METHOD FOR THE PRODUCTION OF DIARYLCYCLOALKYL DERIVATIVES | Sanofi-Aventis Deutschland GmbH (DE) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006021420-A2 | METHOD FOR THE PRODUCTION OF DIARYLCYCLOALKYL DERIVATIVES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2006-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051583-A1 | NOVEL INTERMEDIATE COMPOUNDS USEFUL IN THE PRODUCTION OF DIARYLCYCLOALKYL DERIVATIVES | PPARG, PPARD, PPARA | CA12 4810/4885CA1 4582/4885CA2 4780/4885 |
| US-20070197614-A1 | METHOD FOR THE PRODUCTION OF DIARYLCYCLOALKYL DERIVATIVES | PPARA, PPARD, PPARG | CA12 4762/4885CA1 4523/4885CA2 4573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.