Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 10/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23928128 | 0.81 | NAMPT (0.51) | MAPK1HTT | |
| SCHEMBL23928177 | 0.79 | NPC1 (0.42) | KMT2ASMN1; SMN2TSHRCNR1 | |
| SCHEMBL21382248 | 0.75 | KMT2A (0.57) | GLAKMT2AACHEHDAC3HDAC4 | |
| SCHEMBL4769744 | 0.75 | KMT2A (0.57) | GLAKMT2AACHEMAPK1SMN1; SMN2 | |
| SCHEMBL8585756 | 0.74 | KMT2A (0.56) | GLAKMT2AACHEHDAC3HDAC4 | |
| SCHEMBL5110887 | 0.74 | NPC1 (0.63) | GLAKMT2AACHEGAASMN1; SMN2 | |
| SCHEMBL27887140 | 0.73 | KMT2A (0.55) | GLAKMT2AACHESMN1; SMN2HDAC3 | |
| SCHEMBL7201386 | 0.73 | CNR2 (0.58) | GLAKMT2AACHEADRB3 | |
| SCHEMBL23928131 | 0.73 | NAMPT (0.51) | KMT2AMAPK1HTT | |
| SCHEMBL28364907 | 0.72 | CA1 (0.54) | GLAKMT2AACHEHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3814356-A1 | TRIAZOLOTRIAZINE DERIVATIVES AS A2A RECEPTOR ANTAGONISTS | Zhejiang Vimgreen Pharmaceuticals, Ltd (CN) | 2021-05-05 | — | — | EP | disclosed |