Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | ACHE | P22303 | 12/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | F13A1 | P00488 | 1/20 | 0.55 |
| ▸ | CNR2 | P34972 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.53 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7201386 | 0.94 | CNR2 (0.58) | KMT2AGLAACHEKDM4EF13A1 | |
| SCHEMBL8554270 | 0.93 | ACHE (0.58) | ACHEKDM4ELMNAESR1CYP1A2 | |
| SCHEMBL21382248 | 0.88 | KMT2A (0.57) | KMT2AGLAACHEHDAC3HDAC4 | |
| SCHEMBL8585756 | 0.87 | KMT2A (0.56) | KMT2AGLAACHEHDAC3HDAC4 | |
| SCHEMBL5110887 | 0.87 | NPC1 (0.63) | KMT2AGLAACHELMNASMN1; SMN2 | |
| SCHEMBL8621504 | 0.86 | ACHE (0.59) | ACHEKDM4ELMNAESR1 | |
| SCHEMBL7200875 | 0.86 | ACHE (0.59) | ACHEKDM4ELMNAESR1 | |
| SCHEMBL8624782 | 0.86 | ACHE (0.57) | ACHEKDM4ECNR2LMNAESR1 | |
| SCHEMBL27887140 | 0.86 | KMT2A (0.55) | KMT2AGLAACHESMN1; SMN2HDAC3 | |
| SCHEMBL8590341 | 0.85 | CYP1A2 (0.55) | ACHECNR2LMNAESR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572678-A4 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | ELAN PHARM INC (US) | 2008-05-07 | — | — | EP | disclosed |
| EP-1311625-B1 | FUNCTIONALIZED PERYLENE TETRACARBOXYLIC ACID DIIMIDES | MAX PLANCK GESELLSCHAFT (DE) | 2006-02-01 | — | — | EP | disclosed |
| EP-1572678-A2 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | Elan Pharmaceuticals, Inc. (US) | 2005-09-14 | — | — | EP | disclosed |
| US-6916928-B2 | Functionalized perylene tetracarboxylic acid diimides | MAX-PLANCK-GESELLSCHAFT DER WISSENSCHAFTENE.V. (DE) | 2005-07-12 | — | — | US | disclosed |
| WO-2004056319-A2 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | ELAN PHARMACEUTICALS INC. (US) | 2004-07-08 | — | — | WO | disclosed |
| US-20040024151-A1 | Functionalized perylene tetracarboxylic acid diimides | MAX-PLANCK-GESELLSCHAFT DER WISSENSCHAFTENE. V. (DE) | 2004-02-05 | — | — | US | disclosed |
| CN-1374955-A | Oxazole and thiazole derivatives as antidiabetic and antiobesity agents | BRISTOL MYERS SQUIBB CO (US) | 2002-10-16 | — | — | CN | disclosed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |
| US-4818766-A | ANTIARRHYTHMIA AGENTS, HYPOTENSIVE AGENTS, TREATMENT OF ANGINA | CIBA-GEIGY CORPORATION (US) | 1989-04-04 | — | — | US | disclosed |