Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.58 |
| ▸ | ACHE | P22303 | 14/20 | 0.58 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | TACR2 | P21452 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SHBG | P04278 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4769744 | 0.94 | KMT2A (0.57) | CNR2ACHEESR1KDM4ELMNA | |
| SCHEMBL8621504 | 0.92 | ACHE (0.59) | ACHEESR1ADRA2AADORA3TACR2 | |
| SCHEMBL7200875 | 0.92 | ACHE (0.59) | ACHEESR1ADRA2AADORA3TACR2 | |
| SCHEMBL8624782 | 0.89 | ACHE (0.57) | CNR2ACHEESR1ADRA2AADORA3 | |
| SCHEMBL16790930 | 0.87 | NPC1 (0.60) | ACHELMNAKMT2A | |
| SCHEMBL8554270 | 0.87 | ACHE (0.58) | ACHEESR1ADRA2AADORA3TACR2 | |
| SCHEMBL21382248 | 0.83 | KMT2A (0.57) | ACHEGLAKMT2A | |
| SCHEMBL7192795 | 0.82 | NR5A1 (0.65) | ACHE | |
| SCHEMBL7201443 | 0.82 | NR5A1 (0.65) | ACHETP53 | |
| SCHEMBL580001 | 0.82 | GLA (0.72) | CNR2ESR1KDM4EF13A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596669-B1 | Comprising a support and two reversible heat-sensitive recording layers having different colors formed on the same side of the support, comprising colorless electron-donative dye precursor and an electron-accepting compound | MITSUBISHI PAPER MILLS LIMITED (JP) | 2003-07-22 | — | — | US | disclosed |
| US-6004899-A | SURFACE TREATED WITH SILANE, TITANATE, AND/OR ALUMINUM COUPLING AGENT; PIGMENT; ERASIBILITY | MITSUBISHI PAPER MILLS LIMITED (JP) | 1999-12-21 | — | — | US | disclosed |
| EP-0648612-B1 | Reversible heat-sensitive recording material | MITSUBISHI PAPER MILLS LTD (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5498772-A | SUBSTRATE WITH HEAT SENSITIVE LAYER AND OPTICAL RECORDING LAYER | MITSUBISHI PAPER MILLS LIMITED (JP) | 1996-03-12 | — | — | US | disclosed |
| EP-0648612-A1 | Reversible heat-sensitive recording material | MITSUBISHI PAPER MILLS, LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |