Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12765773 | 0.86 | ALDH1A1 (0.37) | EPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL12765754 | 0.79 | ALDH1A1 (0.34) | EPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL12765501 | 0.77 | ALDH1A1 (0.36) | EPHX2ALDH1A1SMN1; SMN2 | |
| SCHEMBL13717334 | 0.73 | EPHX2 (0.48) | EPHX2TSHRNPSR1 | |
| SCHEMBL12837943 | 0.73 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL192524 | 0.73 | GRIN2D (0.44) | EPHX2SMN1; SMN2TSHR | |
| Idramantone SCHEMBL12496961 | 0.71 | EPHX2 (0.52) | EPHX2ALDH1A1TSHRNPSR1 | |
| Idramantone SCHEMBL3506711 | 0.71 | EPHX2 (0.52) | EPHX2ALDH1A1TSHRNPSR1 | |
| SCHEMBL4368426 | 0.71 | EPHX2 (0.47) | EPHX2TSHRNPSR1 | |
| SCHEMBL22399791 | 0.71 | EPHX2 (0.47) | EPHX2ALDH1A1TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115943144-B | Compound serving as PAK4 kinase inhibitor and preparation method and application thereof | 成都海博为药业有限公司 | 2025-05-13 | — | — | CN | disclosed |
| US-12281092-B2 | Compound or salt thereof, composition, chemiluminescence method, method for measuring chemiluminescence signal, reagent, reagent kit, and method for assaying analyte | SYSMEX CORPORATION (JP) | 2025-04-22 | — | — | US | disclosed |
| CN-117486934-A | Preparation method of chemiluminescent agent and chemiluminescent agent | 苏州亚科科技股份有限公司 | 2024-02-02 | — | — | CN | disclosed |
| US-20230242499-A1 | COMPOUND OR SALT THEREOF, COMPOSITION, CHEMILUMINESCENCE METHOD, METHOD FOR MEASURING CHEMILUMINESCENCE SIGNAL, REAGENT, REAGENT KIT, AND METHOD FOR ASSAYING ANALYTE | SYSMEX CORPORATION (JP) | 2023-08-03 | — | — | US | disclosed |
| US-20230242499-A1 | COMPOUND OR SALT THEREOF, COMPOSITION, CHEMILUMINESCENCE METHOD, METHOD FOR MEASURING CHEMILUMINESCENCE SIGNAL, REAGENT, REAGENT KIT, AND METHOD FOR ASSAYING ANALYTE | SYSMEX CORPORATION (JP) | 2023-08-03 | — | — | US | disclosed |
| US-20230242499-A1 | COMPOUND OR SALT THEREOF, COMPOSITION, CHEMILUMINESCENCE METHOD, METHOD FOR MEASURING CHEMILUMINESCENCE SIGNAL, REAGENT, REAGENT KIT, AND METHOD FOR ASSAYING ANALYTE | SYSMEX CORPORATION (JP) | 2023-08-03 | — | — | US | disclosed |
| EP-4219651-A1 | COMPOUND OR SALT THEREOF, COMPOSITION, CHEMILUMINESCENCE METHOD, METHOD FOR MEASURING CHEMILUMINESCENCE SIGNAL, REAGENT, REAGENT KIT, AND METHOD FOR ASSAYING ANALYTE | SYSMEX CORPORATION (JP) | 2023-08-02 | — | — | EP | disclosed |
| CN-116514869-A | Compound or salt thereof, composition, luminescence method, signal measurement method, reagent, kit, and method for measuring test substance | 希森美康株式会社 | 2023-08-01 | — | — | CN | disclosed |
| CN-115943144-A | Compound serving as PAK4 kinase inhibitor and preparation method and application thereof | 成都海博为药业有限公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-114075175-A | Compound serving as PAK4 kinase inhibitor and preparation method and application thereof | 成都海博为药业有限公司 | 2022-02-22 | — | — | CN | disclosed |
| US-5543295-A | ENZYMATICALLY CLEAVABLE; ANALYZING | TROPIX, INC. (US) | 1996-08-06 | — | — | US | disclosed |
| US-5538847-A | Chemiluminescent 1,2-dioxetanes | TROPIX, INC. (US) | 1996-07-23 | — | — | US | disclosed |
| EP-0649417-A1 | IMPROVED CHEMILUMINESCENT 1,2-DIOXETANES | TROPIX, INC. (US) | 1995-04-26 | — | — | EP | disclosed |
| EP-0649417-A4 | IMPROVED CHEMILUMINESCENT 1,2-DIOXETANES. | TROPIX INC (US) | 1995-02-27 | — | — | EP | disclosed |
| WO-1994026726-A1 | IMPROVED CHEMILUMINESCENT 1,2-DIOXETANES | TROPIX, INC. (US) | 1994-11-24 | — | — | WO | disclosed |
| US-5330900-A | Chemiluminescent 3-(substituted adamant-2'-ylidene) 1,2-dioxetanes | TROPIX, INC. (US) | 1994-07-19 | — | — | US | disclosed |
| US-5326882-A | High speed bioassay | TROPIX, INC. (US) | 1994-07-05 | — | — | US | disclosed |
| EP-0497972-A1 | CHEMILUMINESCENT 3-(SUBSTITUTED ADAMANT-2'-YLIDENE) 1,2-DIOXETANES | TROPIX, INC. (US) | 1992-08-12 | — | — | EP | disclosed |
| US-5112960-A | Enzyme cleavable 1,2-dioxetane compound | APPLIED BIOSYSTEMS, LLC | 1992-05-12 | — | — | US | disclosed |
| WO-1992004341-A1 | CHEMILUMINESCENT 3-(SUBSTITUTED ADAMANT-2'-YLIDENE) 1,2-DIOXETANES | TROPIX, INC. (US) | 1992-03-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12281092-B2 | Compound or salt thereof, composition, chemiluminescence method, method for measuring chemiluminescence signal, reagent, reagent kit, and method for assaying analyte | JAK2, MPO, PEAK1 | EPHX2 1003/4885ALDH1A1 1270/4885SMN1; SMN2 3806/4885 |
| US-20230242499-A1 | COMPOUND OR SALT THEREOF, COMPOSITION, CHEMILUMINESCENCE METHOD, METHOD FOR MEASURING CHEMILUMINESCENCE SIGNAL, REAGENT, REAGENT KIT, AND METHOD FOR ASSAYING ANALYTE | JAK2, MPO, PEAK1 | EPHX2 1003/4885ALDH1A1 1270/4885SMN1; SMN2 3806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.