Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | KIF11 | P52732 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22679506 | 0.87 | POLB (0.47) | POLBALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL8954034 | 0.84 | ALDH1A1 (0.82) | POLBALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL4322427 | 0.79 | KIF11 (0.61) | ALDH1A1TSHRTP53TDP1KIF11 | |
| SCHEMBL23319641 | 0.79 | KIF11 (0.61) | ALDH1A1TSHRTP53TDP1KIF11 | |
| SCHEMBL2231480 | 0.79 | POLB (0.94) | POLBALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL18161362 | 0.79 | KIF11 (0.47) | ALDH1A1TSHRTP53CYP3A4KIF11 | |
| SCHEMBL7240621 | 0.79 | NPC1 (0.49) | POLBALDH1A1TSHRTP53KIF11 | |
| SCHEMBL25515089 | 0.78 | KIF11 (0.50) | ALDH1A1TSHRTP53KIF11NPC1 | |
| SCHEMBL21678295 | 0.78 | KIF11 (0.45) | POLBALDH1A1TSHRTP53TDP1 | |
| SCHEMBL23040384 | 0.78 | KIF11 (0.45) | POLBALDH1A1TSHRTP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1614410-B1 | Dental materials polymerizable by photo-induced ring-opening metathesis polymerization of cyclic olefins | IVOCLAR VIVADENT AG (LI) | 2011-08-10 | — | — | EP | disclosed |
| US-7538172-B2 | Dental materials polymerizable by photo-induced ring-opening metathesis polymerization of cyclic olefins | IVOCLAR VIVADENT AG (LI) | 2009-05-26 | — | — | US | disclosed |
| EP-1614410-A1 | Dental materials polymerizable by photo-induced ring-opening metathesis polymerization of cyclic olefins | Ivoclar Vivadent AG (LI) | 2006-01-11 | — | — | EP | disclosed |
| US-20060004158-A1 | Dental materials polymerizable by photo-induced ring-opening metathesis polymerization of cyclic olefins | IVOCLAR VIVADENT AG (LI) | 2006-01-05 | — | — | US | disclosed |