Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CTH | P32929 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23140063 | 0.83 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2HPGDLMNATDP1 | |
| SCHEMBL7383145 | 0.82 | CTH (0.40) | ALDH1A1SMN1; SMN2HPGDCTHEGLN1 | |
| SCHEMBL7383149 | 0.82 | CTH (0.40) | ALDH1A1SMN1; SMN2HPGDCTHEGLN1 | |
| SCHEMBL11983352 | 0.79 | CTH (0.38) | ALDH1A1SMN1; SMN2HPGDCTHEGLN1 | |
| Aceglumate SCHEMBL29061503 | 0.78 | FOLH1 (0.51) | ALDH1A1SMN1; SMN2MAPTPTGS2NFKB1 | |
| SCHEMBL15482649 | 0.77 | TET2 (0.48) | ALDH1A1SMN1; SMN2HPGDTSHRGAA | |
| SCHEMBL29054450 | 0.77 | KDM4E (0.59) | MAPTPOLB | |
| SCHEMBL17373960 | 0.76 | EGLN1 (0.48) | ALDH1A1CTHEGLN1LMNAMAPT | |
| SCHEMBL24599175 | 0.76 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL23134791 | 0.76 | SMN1; SMN2 (0.40) | ALDH1A1SMN1; SMN2HPGDCYP2C9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 227 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005991-B | Solid anticoagulation microsphere and preparation method and application thereof | 乾德生物医疗技术(广州)有限公司 | 2024-10-15 | — | — | CN | claimed |
| US-12050228-B2 | Automated sample quality assessment | METABOLON, INC. (US) | 2024-07-30 | — | — | US | claimed |
| CN-118005991-A | Solid anticoagulation microsphere and preparation method and application thereof | 乾德生物医疗技术(广州)有限公司 | 2024-05-10 | — | — | CN | claimed |
| US-11906510-B2 | Metabolic profiling by reverse-phase/ion-exchange mass spectrometry | STANFORD JUNIOR UNIVERSITY (US) | 2024-02-20 | — | — | US | claimed |
| CN-116660543-A | Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof | 中国人民解放军陆军军医大学第一附属医院 | 2023-08-29 | — | — | CN | claimed |
| CN-113777189-A | 3-methylcrotonyl coenzyme A carboxylase deficiency detection device and organic acid detection method | 深圳爱湾医学检验实验室 | 2021-12-10 | — | — | CN | claimed |
| EP-3805756-A1 | SMALL MOLECULE BIOCHEMICAL PROFILING OF INDIVIDUAL SUBJECTS FOR DISEASE DIAGNOSIS AND HEALTH ASSESSMENT | Metabolon, Inc. (US) | 2021-04-14 | — | — | EP | claimed |
| US-20210088539-A1 | AUTOMATED SAMPLE QUALITY ASSESSMENT | METABOLON, INC. | 2021-03-25 | — | — | US | claimed |
| US-10890592-B2 | Automated sample quality assessment | METABOLON, INC. (US) | 2021-01-12 | — | — | US | claimed |
| CN-106537145-B | Small molecule biochemical profiling of individual subjects for disease diagnosis and health assessment | 麦特博隆股份有限公司 | 2020-08-25 | — | — | CN | claimed |
| US-8608922-B2 | Biosensor for continuous monitoring of metabolites and proteins and methods of manufacture thereof | THE UNIVERSITY OF CONNECTICUT (US) | 2013-12-17 | — | — | US | claimed |
| US-20130276513-A1 | METHODS FOR DIAGNOSING AND ASSESSING KIDNEY DISEASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2013-10-24 | — | — | US | claimed |
| WO-2013070839-A1 | BIOMARKERS FOR BLADDER CANCER AND METHODS USING THE SAME | METABOLON, INC. (US) | 2013-05-16 | — | — | WO | claimed |
| WO-2012019295-A1 | BIOACTIVE COMPOUNDS IN CAMEL URINE AND MILK | ANTAKLY TONY (CA) | 2012-02-16 | — | — | WO | claimed |
| WO-2011051813-A1 | COMPOSITIONS AND METHODS FOR TREATING DERMATOLOGICAL CONDITIONS | PAUL HARBHAJAN S (US) | 2011-05-05 | — | — | WO | claimed |
| US-20110098229-A1 | COMPOSITIONS AND METHODS FOR TREATING DERMATOLOGICAL CONDITIONS | BIOMED RESEARCH & TECHNOLOGIES, INC. | 2011-04-28 | — | — | US | claimed |
| US-20100116691-A1 | BIOSENSOR FOR CONTINUOUS MONITORING OF METABOLITES AND PROTEINS AND METHODS OF MANUFACTURE THEREOF | UNIVERSITY OF CONNECTICUT (US) | 2010-05-13 | — | — | US | claimed |
| EP-1098630-A2 | COMPOSITION FOR ENHANCING EPIDERMAL LIPID PRODUCTION | Biomed Research and Technologies, Inc. (US) | 2001-05-16 | — | — | EP | claimed |
| US-6149924-A | FOR TOPICAL APPLICATION | BIOMED RESEARCH & TECHNOLOGIES, INC. (US) | 2000-11-21 | — | — | US | claimed |
| WO-2000004870-A2 | COMPOSITION FOR ENHANCING EPIDERMAL LIPID PRODUCTION | BIOMED RESEARCH AND TECHNOLOGIES, INC. (US) | 2000-02-03 | — | — | WO | claimed |