Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.71 |
| ▸ | PROC | P04070 | 2/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 5/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | PLAT | P00750 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2330450 | 0.88 | F10 (0.69) | F10PROCPLGF2PRSS1 | |
| SCHEMBL8623271 | 0.84 | F10 (0.60) | F10PROCPLGF2 | |
| SCHEMBL8629157 | 0.84 | F10 (0.74) | F10PROCPLGF2 | |
| SCHEMBL2326895 | 0.83 | F10 (0.55) | F10PROCPLGF2 | |
| SCHEMBL2328991 | 0.83 | F10 (0.71) | F10PROCPLGF2PRSS1 | |
| SCHEMBL2329338 | 0.83 | F10 (0.55) | F10PROCPLGF2 | |
| SCHEMBL2328900 | 0.82 | F10 (0.70) | F10PROCPLGF2PRSS1 | |
| SCHEMBL2328567 | 0.82 | F10 (0.70) | F10F2 | |
| SCHEMBL2329385 | 0.82 | F10 (0.71) | F10PROCPLGF2PRSS1 | |
| SCHEMBL2329226 | 0.82 | F10 (0.71) | F10PROCPLGF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853618-B1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL -AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA INC (US) | 2011-08-17 | — | — | EP | disclosed |