SCHEMBL8629157

SCHEMBL8629157

N#Cc1cccc(CN2CC[C@H](NS(=O)(=O)c3ccc4c(N)nccc4c3)C2=O)c1

nearest known ligand 0.74

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
F10 P00742 17/20 0.74
F2 P00734 4/20 0.60
PLG P00747 1/20 0.52
PROC P04070 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8623271 0.90 F10 (0.60) F10F2PLGPROC
SCHEMBL28747963 0.85 F10 (1.00) F10F2PLGPROC
SCHEMBL2329362 0.84 F10 (0.71) F10F2PLGPROC
SCHEMBL2329338 0.84 F10 (0.55) F10F2PLGPROC
SCHEMBL2330450 0.84 F10 (0.69) F10F2PLGPROC
SCHEMBL2328991 0.81 F10 (0.71) F10F2PLGPROC
SCHEMBL2328567 0.81 F10 (0.70) F10F2
SCHEMBL2329095 0.80 F10 (0.54) F10F2PLGPROC
SCHEMBL2329385 0.80 F10 (0.71) F10F2PLGPROC
SCHEMBL2329226 0.80 F10 (0.71) F10F2PLGPROC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5731315-A Substituted sulfonic acid n- (aminoiminomethyl)phenylalkyl!-azaheterocyclamide compounds RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1998-03-24 US disclosed