Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 14/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9398456 | 0.85 | GRM2 (0.46) | PIM1GRM2LMNA | |
| SCHEMBL2908140 | 0.84 | KDM4E (0.46) | LMNAACHEKDM4EALDH1A1MAPT | |
| SCHEMBL17821166 | 0.82 | ALDH1A1 (0.48) | GRM2ACHEKDM4EALDH1A1HPGD | |
| SCHEMBL2907490 | 0.79 | GAA (0.51) | LMNALCKKDM4EALDH1A1MAPT | |
| SCHEMBL247555 | 0.77 | GRM2 (0.59) | GRM2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL17769122 | 0.76 | GRM2 (0.57) | GRM2ALDH1A1 | |
| SCHEMBL2910010 | 0.73 | MGAM (0.42) | LMNAACHEKDM4EALDH1A1HPGD | |
| SCHEMBL11069574 | 0.73 | KDM4E (0.46) | PIM1GRM2LCKKDM4EMAPT | |
| SCHEMBL5211310 | 0.72 | PIM1 (0.60) | PIM1GRM2HTR2BLMNAACHE | |
| SCHEMBL27401567 | 0.70 | GRM2 (0.65) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11712425-B2 | Immunoregulatory role of 3-OH-kynurenamine and uses thereof | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2023-08-01 | — | — | US | disclosed |
| US-20210008021-A1 | IMMUNOREGULATORY ROLE OF 3-OH-KYNURENAMINE AND USES THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2021-01-14 | — | — | US | disclosed |
| WO-2019178013-A1 | IMMUNOREGULATORY ROLE OF 3-OH-KYNURENAMINE AND USES THEREOF | ALBERT EINSTEIN COLLEGE OF MEDICINE (US) | 2019-09-19 | — | — | WO | disclosed |
| US-9673030-B2 | Computer readable storage mediums, methods and systems for normalizing chemical profiles in biological or medical samples detected by mass spectrometry | EMORY UNIVERSITY (US) | 2017-06-06 | — | — | US | disclosed |
| EP-2279417-B1 | METABOLIC BIOMARKERS FOR OVARIAN CANCER AND METHODS OF USE THEREOF | GEORGIA TECH RES INST (US) | 2016-07-20 | — | — | EP | disclosed |
| US-20140309186-A1 | Metabolomics-Based Identification of Disease-Causing Agents | GEORGIA TECH RESEARCH CORPORATION | 2014-10-16 | — | — | US | disclosed |
| US-20120191434-A1 | ARTICLES OF MANUFACTURE AND METHODS FOR MODELING CHINESE HAMSTER OVARY (CHO) CELL METABOLISM | GT LIFE SCIENCES, INC. (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120004854-A1 | METABOLIC BIOMARKERS FOR OVARIAN CANCER AND METHODS OF USE THEREOF | GEORGIA TECH RESEARCH CORPORATION | 2012-01-05 | — | — | US | disclosed |
| US-20110282587-A1 | COMPUTER READABLE STORAGE MEDIUMS, METHODS AND SYSTEMS FOR NORMALIZING CHEMICAL PROFILES IN BIOLOGICAL OR MEDICAL SAMPLES DETECTED BY MASS SPECTROMETRY | EMORY UNIVERSITY (US) | 2011-11-17 | — | — | US | disclosed |
| US-20110246081-A1 | Metabolomics-Based Identification of Disease-Causing Agents | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-10-06 | — | — | US | disclosed |
| EP-1644316-B1 | 2-AMINOBENZOYL DERIVATIVES | NEURIM PHARMA 1991 (IL) | 2010-03-10 | — | — | EP | disclosed |
| CN-1196681-C | (+)-Norcisapride useful for 5-HT3 and 5-HT4 mediated disorbers | JANSSEN PHARMACEUTICA NV (BE) | 2005-04-13 | — | — | CN | disclosed |
| CN-1262675-A | (+)-Norcisapride useful for 5-HT3 and 5-HT4 mediated disorbers | JANSSEN PHARMACEUTICA NV (BE) | 2000-08-09 | — | — | CN | disclosed |