Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | COMT | P21964 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11069571 | 0.84 | KDM4E (0.41) | KDM4EPRMT5NPC1RAB9AMAPT | |
| SCHEMBL5257685 | 0.75 | KDM4E (0.50) | KDM4EPRMT5NPC1RAB9AMAPT | |
| SCHEMBL247555 | 0.75 | GRM2 (0.59) | GRM2 | |
| Hydrochloric Acid SCHEMBL17769122 | 0.73 | GRM2 (0.57) | GRM2 | |
| SCHEMBL232938 | 0.73 | PIM1 (0.47) | KDM4EPIM1GRM2MAPTTSHR | |
| SCHEMBL6636369 | 0.73 | PRMT5 (0.50) | KDM4EPRMT5NPC1RAB9AMAPT | |
| SCHEMBL30625771 | 0.73 | MMP2 (0.46) | KDM4EPRMT5NPC1RAB9AMAPT | |
| SCHEMBL163181 | 0.73 | ALDH1A1 (0.46) | KDM4EPARP1PIM1NPC1RAB9A | |
| SCHEMBL28008057 | 0.73 | METAP2 (0.46) | KDM4EPRMT5NPC1RAB9AMAPT | |
| Hydrochloric Acid SCHEMBL27739681 | 0.71 | ALDH1A1 (0.44) | KDM4EPARP1PIM1GRM2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353824-A | DETECTORS OF BETA-LACTAMASES | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-10-12 | — | — | US | claimed |
| US-4448880-A | Detection of β-lactamase utilizing a chromophoric cephalosporin composition | HOECHST AG. (DE) | 1984-05-15 | — | — | US | disclosed |
| US-4353824-A | DETECTORS OF BETA-LACTAMASES | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-10-12 | — | — | US | disclosed |