Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.59 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | KMO | O15229 | 3/20 | 0.56 |
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | RXRB | P28702 | 1/20 | 0.55 |
| ▸ | ERN1 | O75460 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.52 |
| ▸ | ACLY | P53396 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | TPMT | P51580 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12171455 | 0.87 | MYC (0.57) | PDE4APDE4BPDE4CPDE4DKMO | |
| SCHEMBL5151529 | 0.86 | PDE4A (0.71) | PDE4APDE4BPDE4CPDE4DKMO | |
| SCHEMBL28525131 | 0.83 | NR4A2 (0.68) | MRGPRX4RAB9ASMN1; SMN2 | |
| SCHEMBL308170 | 0.82 | TPMT (0.69) | LMNATTRMRGPRX4CA12CA1 | |
| SCHEMBL29524334 | 0.82 | TPMT (0.69) | LMNATTRMRGPRX4CA12CA1 | |
| SCHEMBL7611643 | 0.82 | PDE4A (0.59) | PDE4APDE4BPDE4CPDE4DKMO | |
| SCHEMBL5149280 | 0.82 | LMNA (0.69) | PDE4APDE4BPDE4CPDE4DKMO | |
| SCHEMBL1812435 | 0.81 | KMO (0.55) | PDE4BPDE4DKMOTTRACLY | |
| SCHEMBL3540530 | 0.80 | KMO (0.66) | KMORXRARXRBERN1LMNA | |
| Hydrochloric Acid SCHEMBL306990 | 0.80 | CA12 (0.67) | LMNATTRMRGPRX4CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11214564-B2 | Compounds with thymine skeleton for use in medicine | Technische Universität Dresden (DE) | 2022-01-04 | — | — | US | disclosed |
| US-11214564-B2 | Compounds with thymine skeleton for use in medicine | Technische Universität Dresden (DE) | 2022-01-04 | — | — | US | disclosed |
| EP-3819006-A1 | COMPOUNDS WITH THYMINE SKELETON FOR USE IN MEDICINE | Technische Universität Dresden (DE) | 2021-05-12 | — | — | EP | disclosed |
| EP-3819006-A1 | COMPOUNDS WITH THYMINE SKELETON FOR USE IN MEDICINE | Technische Universität Dresden (DE) | 2021-05-12 | — | — | EP | disclosed |
| US-20210130328-A1 | NOVEL COMPOUNDS WITH THYMINE SKELETON FOR USE IN MEDICINE | Technische Universität Dresden (DE) | 2021-05-06 | — | — | US | disclosed |
| US-20210130328-A1 | NOVEL COMPOUNDS WITH THYMINE SKELETON FOR USE IN MEDICINE | Technische Universität Dresden (DE) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210130328-A1 | NOVEL COMPOUNDS WITH THYMINE SKELETON FOR USE IN MEDICINE | TMSB10, TMSB4X, TBCA | PDE4A 3614/4885PDE4B 3693/4885PDE4C 3627/4885 |
| US-11214564-B2 | Compounds with thymine skeleton for use in medicine | TMSB10, TMSB4X, TBCA | PDE4A 3754/4885PDE4B 3829/4885PDE4C 3807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.