Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38651084 | 0.78 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL29310752 | 0.75 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL28963242 | 0.75 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL10635589 | 0.74 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL29176333 | 0.74 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL16875634 | 0.74 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL31121930 | 0.73 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL28551883 | 0.72 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL2368119 | 0.70 | PTGS1 (0.34) | ALDH1A1 | |
| SCHEMBL15969015 | 0.69 | PSEN1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667621-B2 | Antiestrogen compounds | STEVENS INSTITUTE OF TECHNOLOGY (US) | 2023-06-06 | — | — | US | disclosed |
| US-20210130320-A1 | ANTIESTROGEN COMPOUNDS | STEVENS INSTITUTE OF TECHNOLOGY (US) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11667621-B2 | Antiestrogen compounds | ESR1, ESR2, ESRRG | ALDH1A1 4268/4885 |
| US-20210130320-A1 | ANTIESTROGEN COMPOUNDS | ESR1, ESR2, ESRRG | ALDH1A1 4268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.