Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14336109 | 0.91 | ALOX5 (0.33) | SMYD3 | |
| SCHEMBL13775302 | 0.91 | ALOX5 (0.33) | SMYD3 | |
| SCHEMBL28723085 | 0.91 | ALOX5 (0.33) | SMYD3 | |
| SCHEMBL4938530 | 0.91 | ALOX5 (0.33) | SMYD3 | |
| SCHEMBL18987904 | 0.91 | ALOX5 (0.33) | SMYD3 | |
| SCHEMBL8227849 | 0.91 | ALOX5 (0.33) | SMYD3 | |
| Hydrochloric Acid SCHEMBL4933747 | 0.88 | ALOX5 (0.32) | SMYD3KDM4EGMNNLMNAMAPT | |
| Hydrochloric Acid SCHEMBL18988009 | 0.88 | ALOX5 (0.32) | SMYD3KDM4EGMNNLMNAMAPT | |
| Hydrochloric Acid SCHEMBL21222289 | 0.88 | ALOX5 (0.32) | SMYD3KDM4EGMNNLMNAMAPT | |
| Hydrochloric Acid SCHEMBL4933740 | 0.88 | ALOX5 (0.32) | SMYD3KDM4EGMNNLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3812387-A1 | HETEROCYCLIC PROTEIN KINASE INHIBITORS | Sumitomo Dainippon Pharma Oncology, Inc. (US) | 2021-04-28 | — | — | EP | disclosed |