Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.60 |
| ▸ | PYGM | P11217 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2292518 | 0.92 | SERPINE1 (0.71) | MEN1KMT2APKMSERPINE1NPC1 | |
| SCHEMBL30466712 | 0.90 | MEN1 (0.72) | MEN1KMT2APKMSERPINE1NPC1 | |
| SCHEMBL2025586 | 0.90 | MEN1 (0.72) | MEN1KMT2APKMSERPINE1NPC1 | |
| SCHEMBL2290709 | 0.89 | SERPINE1 (0.76) | MEN1KMT2APKMSERPINE1NPC1 | |
| SCHEMBL2288393 | 0.89 | MAPK1 (0.67) | MEN1KMT2APKMSERPINE1NPC1 | |
| SCHEMBL2293458 | 0.89 | PGR (0.67) | MEN1KMT2APKMSERPINE1NPC1 | |
| SCHEMBL2291684 | 0.89 | SERPINE1 (0.61) | MEN1KMT2APKMSERPINE1NPC1 | |
| SCHEMBL6408811 | 0.87 | MEN1 (0.64) | MEN1KMT2APKMSERPINE1NPC1 | |
| SCHEMBL2271588 | 0.86 | SERPINE1 (0.64) | MEN1KMT2APKMSERPINE1NPC1 | |
| SCHEMBL8027764 | 0.86 | MEN1 (0.67) | MEN1KMT2APKMSERPINE1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011097600-A1 | SCREENING METHOD AND COMPOUNDS FOR MODULATING TELOMERASE ACTIVITY | THE WISTAR INSTITUTE (US) | 2011-08-11 | — | — | WO | disclosed |