SCHEMBL2271588

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2274898	0.93	SERPINE1 (0.60)	SERPINE1MEN1KMT2ATDP1PKM
	SCHEMBL2276745	0.92	SERPINE1 (0.65)	SERPINE1MEN1KMT2ATDP1PYGL
	SCHEMBL2273044	0.92	CYP2C9 (0.61)	SERPINE1MEN1KMT2ATDP1PKM
	SCHEMBL2270621	0.92	GALK1 (0.68)	SERPINE1TDP1PYGLPYGMHPSE
	SCHEMBL2272706	0.92	MEN1 (0.67)	SERPINE1MEN1KMT2ATDP1PKM
	SCHEMBL2272347	0.92	SERPINE1 (0.69)	SERPINE1MEN1KMT2ATDP1PKM
	SCHEMBL2274811	0.92	PYGM (0.57)	SERPINE1MEN1KMT2ATDP1PKM
	SCHEMBL2272043	0.91	SERPINE1 (0.75)	SERPINE1MEN1KMT2ATDP1PKM
	SCHEMBL2275467	0.91	CYP2C9 (0.63)	SERPINE1MEN1KMT2ATDP1PKM
	SCHEMBL2271007	0.91	MEN1 (0.69)	SERPINE1MEN1KMT2APKMPYGM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.