SCHEMBL2330388

SCHEMBL2330388

CSCC[C@H](NC(=O)c1c(C(=O)O)ccc2ccccc12)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FNTA P49354 7/20 0.49
FNTB P49356 7/20 0.49
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
ALDH1A1 P00352 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
CA2 P00918 2/20 0.46
CA1 P00915 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2330414 0.92 FNTA (0.51) FNTAFNTBMEN1KMT2AALDH1A1
SCHEMBL2327913 0.87 FNTA (0.50) FNTAFNTBMEN1KMT2AALDH1A1
SCHEMBL2327241 0.87 ALDH1A1 (0.52) FNTAFNTBMEN1KMT2AALDH1A1
SCHEMBL2330795 0.87 FNTA (0.50) FNTAFNTBMEN1KMT2AALDH1A1
SCHEMBL27974453 0.86 FNTA (0.49) FNTAFNTBMEN1KMT2AALDH1A1
SCHEMBL2334486 0.86 FNTA (0.49) FNTAFNTBMEN1KMT2AALDH1A1
SCHEMBL2331103 0.84 LMNA (0.53) FNTAFNTBMEN1KMT2AALDH1A1
SCHEMBL9828951 0.83 FNTA (0.62) FNTAFNTBMEN1KMT2AALDH1A1
SCHEMBL2324069 0.83 FNTA (0.62) FNTAFNTBMEN1KMT2AALDH1A1
SCHEMBL2329890 0.80 ALDH1A1 (0.56) FNTAFNTBALDH1A1NPSR1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2356979-B1 ANTI-WRINKLE AGENTS POLA CHEM IND INC (JP) 2017-10-25 EP disclosed
EP-3173063-A1 ANTI-WRINKLE AGENTS Pola Chemical Industries Inc. (JP) 2017-05-31 EP disclosed
US-8835498-B2 Anti-wrinkle agents POLA CHEMICAL INDUSTRIES INC. (JP) 2014-09-16 US disclosed
US-20110245343-A1 ANTI-WRINKLE AGENTS POLA CHEMICAL INDUSTRIES INC. (JP) 2011-10-06 US disclosed
EP-2356979-A1 ANTI-WRINKLE AGENTS Pola Chemical Industries Inc. (JP) 2011-08-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110245343-A1 ANTI-WRINKLE AGENTS GLA, H1-4, H1-3 FNTA 4644/4885FNTB 4431/4885MEN1 4082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.