⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3611106 | 0.74 | — | — | |
| SCHEMBL30337062 | 0.68 | — | — | |
| SCHEMBL30826379 | 0.67 | — | — | |
| SCHEMBL15830347 | 0.67 | — | — | |
| SCHEMBL3608596 | 0.67 | LMNA (0.42) | — | |
| SCHEMBL3604842 | 0.67 | LMNA (0.42) | — | |
| Hydrogen Sulfide SCHEMBL3608592 | 0.67 | LMNA (0.42) | — | |
| Cinnoline SCHEMBL28244175 | 0.65 | RAB9A (0.39) | — | |
| SCHEMBL2009457 | 0.64 | — | — | |
| SCHEMBL14438004 | 0.64 | NTRK1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122103165-A | Thieno [2,3-c ] pyridazine derivatives as positive allosteric modulators of cholinergic M4 receptors | — | 2026-05-29 | — | — | CN | disclosed |
| US-12012467-B2 | Small molecule DCN1 inhibitors and therapeutic methods using the same | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-18 | — | — | US | disclosed |
| CN-114920911-B | Method for producing polyisothiaindene conductive polymer | 株式会社力森诺科 | 2024-05-03 | — | — | CN | disclosed |
| CN-114787166-B | Crystal forms of thieno [2,3-c ] pyridazine-4 (1H) -ketone compound, and preparation method and application thereof | 漳州片仔癀药业股份有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-114787166-B | Crystal forms of thieno [2,3-c ] pyridazine-4 (1H) -ketone compound, and preparation method and application thereof | 漳州片仔癀药业股份有限公司 | 2023-09-19 | — | — | CN | disclosed |
| US-20230277534-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC. | 2023-09-07 | — | — | US | disclosed |
| EP-4219465-A2 | PRMT5 INHIBITORS AND USES THEREOF | Epizyme Inc (US) | 2023-08-02 | — | — | EP | disclosed |
| US-20230192617-A1 | AZABICYCLIC(THIO)AMIDES AS FUNGICIDAL COMPOUNDS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2023-06-22 | — | — | US | disclosed |
| CN-116041365-A | Muscarinic acetylcholine receptorsBody M 4 Positive allosteric modulators of (2) | 范德比尔特大学 | 2023-05-02 | — | — | CN | disclosed |
| EP-4153566-A1 | AZABICYCLIC(THIO)AMIDES AS FUNGICIDAL COMPOUNDS | Bayer CropScience Aktiengesellschaft (DE) | 2023-03-29 | — | — | EP | disclosed |
| WO-2007027855-A2 | RAF INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2007-03-08 | — | — | WO | disclosed |
| WO-2007027855-A2 | RAF INHIBITOR COMPOUNDS AND METHODS OF USE THEREOF | ARRAY BIOPHARMA INC. (US) | 2007-03-08 | — | — | WO | disclosed |
| US-20070049603-A1 | Raf inhibitor compounds and methods of use thereof | ARRAY BIOPHARMA INC. | 2007-03-01 | — | — | US | disclosed |
| US-20070049603-A1 | Raf inhibitor compounds and methods of use thereof | ARRAY BIOPHARMA INC. | 2007-03-01 | — | — | US | disclosed |
| EP-0842178-B1 | FUROPYRIDINE, THIENOPYRIDINE, PYRROLOPYRIDINE AND RELATED PYRIMIDINE, PYRIDAZINE AND TRIAZINE COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LAB (US) | 2001-03-28 | — | — | EP | disclosed |
| EP-0973777-A1 | FUROPYRIDINE, THIENOPYRIDINE, PYRROLOPYRIDINE AND RELATED PYRIMIDINE, PYRIDAZINE AND TRIAZINE COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 2000-01-26 | — | — | EP | disclosed |
| US-6001849-A | Furopyridine, thienopyridine pyrrolopyridine useful in controlling chemical synaptic transmission | ABBOTT LABORATORIES (US) | 1999-12-14 | — | — | US | disclosed |
| WO-1998046609-A1 | FUROPYRIDINE, THIENOPYRIDINE, PYRROLOPYRIDINE AND RELATED PYRIMIDINE, PYRIDAZINE AND TRIAZINE COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1998-10-22 | — | — | WO | disclosed |
| EP-0842178-A1 | FUROPYRIDINE, THIENOPYRIDINE, PYRROLOPYRIDINE AND RELATED PYRIMIDINE, PYRIDAZINE AND TRIAZINE COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997005139-A1 | FUROPYRIDINE, THIENOPYRIDINE, PYRROLOPYRIDINE AND RELATED PYRIMIDINE, PYRIDAZINE AND TRIAZINE COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 1997-02-13 | — | — | WO | disclosed |