Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.32 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | ACR | P10323 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15808661 | 1.00 | KDM4E (0.38) | KDM4ECYP2D6CYP2C19ALDH1A1TGFBR1 | |
| SCHEMBL10777363 | 0.85 | CYP2D6 (0.42) | KDM4ECYP2D6CYP2C19ALDH1A1MEN1 | |
| SCHEMBL5001767 | 0.83 | CYP2D6 (0.54) | KDM4ECYP2D6CYP2C19ALDH1A1TGFBR1 | |
| SCHEMBL28967955 | 0.81 | KDM4E (0.38) | KDM4ECYP2D6CYP2C19ALDH1A1TGFBR1 | |
| SCHEMBL536399 | 0.80 | TGFBR1 (0.37) | KDM4ETGFBR1GAA | |
| SCHEMBL1318824 | 0.80 | — | — | |
| SCHEMBL31286067 | 0.80 | — | — | |
| SCHEMBL12521641 | 0.80 | — | — | |
| SCHEMBL17183910 | 0.78 | CYP2D6 (0.42) | KDM4ECYP2D6CYP2C19ALDH1A1MEN1 | |
| SCHEMBL29256341 | 0.77 | KDM4E (0.44) | KDM4EALDH1A1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115353853-A | Two-component polyurethane adhesive and preparation method and application thereof | 杭州之江有机硅化工有限公司 | 2022-11-18 | — | — | CN | claimed |
| CN-117956984-A | Novel microparticles containing active substances | 巴斯夫欧洲公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-117642168-A | Inhibitors of bruton's tyrosine kinase and methods of use thereof | 詹森药业有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-117083058-A | Solid SNEDDS based on specific mixtures of acrylic polymers | 赢创运营有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-116847875-A | Active cancer immunotherapy by immunomodulation via GLOBO series antigens | 台湾浩鼎生技股份有限公司 | 2023-10-03 | — | — | CN | disclosed |
| CN-115353853-A | Two-component polyurethane adhesive and preparation method and application thereof | 杭州之江有机硅化工有限公司 | 2022-11-18 | — | — | CN | disclosed |
| EP-3008517-A1 | A LITHOGRAPHIC PRINTING PLATE PRECURSOR | Agfa Graphics N.V. (BE) | 2016-04-20 | — | — | EP | disclosed |
| WO-2014198820-A1 | A LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA GRAPHICS NV (BE) | 2014-12-18 | — | — | WO | disclosed |
| WO-2011097600-A1 | SCREENING METHOD AND COMPOUNDS FOR MODULATING TELOMERASE ACTIVITY | THE WISTAR INSTITUTE (US) | 2011-08-11 | — | — | WO | disclosed |
| US-4645853-A | Hindered phenolic oxamide compounds and stabilized compositions | ICI AMERICAS INC. (US) | 1987-02-24 | — | — | US | disclosed |