SCHEMBL536399

SCHEMBL536399

NC(=O)C(=O)NCC(O)O

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.37
KDM4E B2RXH2 1/20 0.36
GAA P10253 1/20 0.32
BCAT2 O15382 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiodiglycol SCHEMBL6850647 0.84 TDP1 (0.37) TGFBR1
SCHEMBL561651 0.83 KMT2A (0.34) KDM4E
SCHEMBL15808661 0.80 KDM4E (0.38) TGFBR1KDM4EGAA
SCHEMBL2330624 0.80 KDM4E (0.38) TGFBR1KDM4EGAA
SCHEMBL538750 0.78
SCHEMBL13857911 0.77 TGFBR1 (0.35) TGFBR1KDM4EGAA
SCHEMBL5001767 0.77 CYP2D6 (0.54) TGFBR1KDM4EGAA
SCHEMBL29256341 0.77 KDM4E (0.44) TGFBR1KDM4E
SCHEMBL28967955 0.75 KDM4E (0.38) TGFBR1KDM4EGAA
SCHEMBL8424312 0.72 ALDH1A1 (0.32) BCAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 724 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119823344-A Stress-induced material and preparation method thereof 华中科技大学 2025-04-15 CN claimed
CN-118006093-A Polyethylene glycol succinate compound and preparation method thereof 中国石油大学(北京) 2024-05-10 CN claimed
WO-2023062053-A1 PROCESS FOR SYNTHESIZING BIS(2-NITRATOETHYL) DINITROXAMIDE EURENCO (FR) 2023-04-20 WO claimed
EP-4166536-A1 PROCESS FOR SYNTHESIZING BIS(2-NITRATOETHYL) DINITROXAMIDE Eurenco (FR) 2023-04-19 EP claimed
CN-115627079-A High-viscosity emulsified asphalt and preparation method thereof 厦门新立基股份有限公司 2023-01-20 CN claimed
EP-0142467-B1 POLYMER COMPOUNDS CONTAINING PIPERIDYL GROUPS AND THEIR USE AS STABILISERS IN SYNTHETIC POLYMERS CIBA-GEIGY S.p.A. (IT) 1988-08-24 EP claimed
US-6391949-B1 None US disclosed
EP-4536463-B1 PROCESS TO PREPARE THERMOPLASTIC COMPOSITIONS COMPRISING FLUORINE FREE POLYMER PROCESSING AIDS NOVA CHEMICALS INTERNATIONAL SA (CH) 2026-05-13 EP disclosed
EP-4728007-A1 NON-FLUORINATED POLYMER PROCESS AIDS Nova Chemicals (International) S.A. (CH) 2026-04-22 EP disclosed
US-20260070275-A1 FLUOROPOLYMER FREE POLYMER PROCESSING AIDS NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2026-03-12 US disclosed
EP-4692239-A2 BLOCK COPOLYMER POLYMER PROCESSING AIDS Nova Chemicals (International) S.A. (CH) 2026-02-11 EP disclosed
EP-4674909-A1 FLUORINE FREE POLYMER PROCESSING AIDS Nova Chemicals (International) S.A. (CH) 2026-01-07 EP disclosed
US-12502818-B2 Fluoropolymer free polymer processing aids NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2025-12-23 US disclosed
US-4419472-A FOR PLASTICS CIBA-GEIGY CORPORATION (US) 1983-12-06 US disclosed
EP-0094350-A2 1-Diorganocarbamoyl-polyalkyl piperidines and their preparation CIBA-GEIGY AG (CH) 1983-11-16 EP disclosed
EP-0090770-A1 Phosphoric-acid compounds as costabilizers for Me(II) carboxylates and/or Me(II) phenolates in polyvinyl chloride CIBA-GEIGY AG (CH) 1983-10-05 EP disclosed
EP-0083308-A1 Process for stabilising fungicides CIBA-GEIGY AG (CH) 1983-07-06 EP disclosed
EP-0081457-A2 Phenols and their uses as stabilizers CIBA-GEIGY AG (CH) 1983-06-15 EP disclosed
US-4366280-A ELASTOMERS MODIFIED BY CALCIUM STEAROYL LACTATE OR DERIVATIVES; HEAT AND EXIDATION RESISTANCE K.K. MUSASHINO KAGAKU KENKYUSHO (JP) 1982-12-28 US disclosed
EP-0052579-A1 Stabilisers against photo degradation CIBA-GEIGY AG (CH) 1982-05-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070275-A1 FLUOROPOLYMER FREE POLYMER PROCESSING AIDS PFKP, LCP1, PIGK TGFBR1 3439/4885KDM4E 1004/4885GAA 498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.