Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6223489 | 1.00 | SLC6A3 (0.36) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| Hydrochloric Acid SCHEMBL902096 | 0.98 | ALDH1A1 (0.38) | SLC6A3SLC6A2ALDH1A1LMNATSHR | |
| SCHEMBL9685631 | 0.94 | SLC6A3 (0.42) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| Hydrochloric Acid SCHEMBL8933166 | 0.92 | SLC6A3 (0.43) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL27508951 | 0.91 | MEN1 (0.40) | LMNATSHRMEN1BLMKMT2A | |
| Hydrochloric Acid SCHEMBL10369158 | 0.83 | ALDH1A1 (0.34) | SLC6A3SLC6A2ALDH1A1LMNATSHR | |
| SCHEMBL9998422 | 0.83 | EPHX1 (0.36) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| Hydrochloric Acid SCHEMBL8722589 | 0.83 | ALDH1A1 (0.34) | SLC6A3SLC6A2ALDH1A1LMNATSHR | |
| Ammonia Solution, Strong SCHEMBL16191692 | 0.81 | EPHX1 (0.35) | SLC6A3SLC6A2SLC6A4DHFRALDH1A1 | |
| SCHEMBL4014963 | 0.79 | ALDH1A1 (0.43) | SLC6A3SLC6A2SLC6A4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356110-B1 | QUINAZOLINAMIDE DERIVATIVES | MERCK PATENT GMBH (DE) | 2016-01-06 | — | — | EP | disclosed |
| EP-2383267-A1 | Substituted sulfonamide derivatives | Grünenthal GmbH (DE) | 2011-11-02 | — | — | EP | disclosed |
| EP-2356110-A1 | QUINAZOLINAMIDE DERIVATIVES | Merck Patent GmbH (DE) | 2011-08-17 | — | — | EP | disclosed |
| EP-1904497-B1 | SUBSTITUTED RYLENE DERIVATIVES | BASF SE (DE) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010066324-A1 | QUINAZOLINAMIDE DERIVATIVES | MERCK PATENT GMBH (DE) | 2010-06-17 | — | — | WO | disclosed |
| EP-2086935-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVES FOR USE AS BRADYKININ 1 RECEPTOR MODULATORS | Grünenthal GmbH (DE) | 2009-08-12 | — | — | EP | disclosed |
| EP-2066659-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2009-06-10 | — | — | EP | disclosed |
| EP-2007857-A1 | USE OF RYLENES AS MARKERS FOR LIQUIDS | BASF SE (DE) | 2008-12-31 | — | — | EP | disclosed |
| WO-2008046573-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVES FOR USE AS BRADYKININ 1 RECEPTOR MODULATORS | Grünenthal GmbH (DE) | 2008-04-24 | — | — | WO | disclosed |
| WO-2008040492-A1 | SUBSTITUTED SULFONAMIDE DERIVATIVES | Grünenthal GmbH (DE) | 2008-04-10 | — | — | WO | disclosed |
| EP-1904497-A1 | SUBSTITUTED RYLENE DERIVATIVES | BASF SE (DE) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007099059-A1 | USE OF RYLENES AS MARKERS FOR LIQUIDS | BASF SE (DE) | 2007-09-07 | — | — | WO | disclosed |
| EP-1819678-A1 | RYLENE TETRACARBOXYLIC ACID DIIMIDES SUBSTITUTED BY CYCLIC AMINO GROUPS | BASF AKTIENGESELLSCHAFT (DE) | 2007-08-22 | — | — | EP | disclosed |
| WO-2007006717-A1 | SUBSTITUTED RYLENE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2007-01-18 | — | — | WO | disclosed |
| WO-2006058674-A1 | RYLENE TETRACARBOXYLIC ACID DIIMIDES SUBSTITUTED BY CYCLIC AMINO GROUPS | BASF AKTIENGESELLSCHAFT (DE) | 2006-06-08 | — | — | WO | disclosed |