SCHEMBL23308243

SCHEMBL23308243

Clc1cccc(-c2ccc(N(c3ccccc3)c3ccccc3)cc2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.52
ALOX5 P09917 1/20 0.48
MAOB P27338 2/20 0.47
CYP1A2 P05177 2/20 0.46
ESR2 Q92731 2/20 0.44
NPC1 O15118 1/20 0.44
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44
NFKB1 P19838 1/20 0.44
RAB9A P51151 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
BACE1 P56817 1/20 0.44
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
MAPT P10636 1/20 0.42
CYP2C9 P11712 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26306459 1.00 TAAR1 (0.52) TAAR1ALOX5MAOBCYP1A2ESR2
SCHEMBL15713960 0.93 TAAR1 (0.44) TAAR1ALOX5MAOBCYP1A2ESR2
SCHEMBL20872019 0.92 CYP1A2 (0.46) TAAR1ALOX5MAOBCYP1A2ESR2
SCHEMBL9581080 0.92 CYP1A2 (0.46) TAAR1ALOX5MAOBCYP1A2ESR2
SCHEMBL16858263 0.92 CYP1A2 (0.46) TAAR1ALOX5MAOBCYP1A2ESR2
SCHEMBL12533861 0.92 CYP1A2 (0.46) TAAR1ALOX5MAOBCYP1A2ESR2
SCHEMBL19801911 0.91 CYP1A2 (0.45) TAAR1ALOX5MAOBCYP1A2NPC1
SCHEMBL20872026 0.90 NPC1 (0.46) TAAR1ALOX5MAOBESR2NPC1
SCHEMBL20964252 0.90 NPC1 (0.46) TAAR1ALOX5MAOBESR2NPC1
SCHEMBL512533 0.90 MAPT (0.44) TAAR1ALOX5MAOBCYP1A2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210126204-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2021-04-29 US disclosed