Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1702986 | 1.00 | MAPT (0.44) | MAPTALDH1A1CYP1A2TDP1L3MBTL1 | |
| SCHEMBL258156 | 1.00 | MAPT (0.44) | MAPTALDH1A1CYP1A2TDP1L3MBTL1 | |
| SCHEMBL12533861 | 0.98 | CYP1A2 (0.46) | MAPTALDH1A1CYP1A2TDP1L3MBTL1 | |
| SCHEMBL9581080 | 0.98 | CYP1A2 (0.46) | MAPTALDH1A1CYP1A2TDP1L3MBTL1 | |
| SCHEMBL20872019 | 0.98 | CYP1A2 (0.46) | MAPTALDH1A1CYP1A2TDP1L3MBTL1 | |
| SCHEMBL16858263 | 0.98 | CYP1A2 (0.46) | MAPTALDH1A1CYP1A2TDP1L3MBTL1 | |
| SCHEMBL19801911 | 0.96 | CYP1A2 (0.45) | MAPTALDH1A1CYP1A2TDP1L3MBTL1 | |
| SCHEMBL15713960 | 0.94 | TAAR1 (0.44) | MAPTALDH1A1CYP1A2TDP1L3MBTL1 | |
| SCHEMBL8100812 | 0.94 | MAPT (0.48) | MAPTALDH1A1CYP1A2TDP1L3MBTL1 | |
| SCHEMBL9321690 | 0.92 | MAPT (0.50) | MAPTALDH1A1CYP1A2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120028180-A1 | SPIRODILACTAM POLYCARBONATE CONTAINING PHOTOCONDUCTORS | XEROX CORPORATION (US) | 2012-02-02 | — | — | US | disclosed |
| US-7622231-B2 | Imaging members containing intermixed polymer charge transport component layer | XEROX CORPORATION (US) | 2009-11-24 | — | — | US | disclosed |
| US-7534536-B2 | Photoconductor containing substrate, undercoat layer thereover comprising polyol resin, aminoplast resin, polyarylate, siloxane modified polyarylate, epoxy modified polyarylate, or urethane modified polyarylate, or amine modified polyarylate, metal oxide, photogenerating layer, and charge transport layer | XEROX CORPORATION (US) | 2009-05-19 | — | — | US | disclosed |
| US-20080057426-A1 | Photoconductors | XEROX CORPORATION | 2008-03-06 | — | — | US | disclosed |