Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 11/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 9/20 | 0.47 |
| ▸ | ITGB7 | P26010 | 8/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PYGL | P06737 | 2/20 | 0.46 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ITGAV | P06756 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2330851 | 1.00 | ITGB1 (0.47) | ITGB1ITGA4ITGB7POLBPYGL | |
| SCHEMBL13583835 | 0.89 | ITGB1 (0.44) | ITGB1ITGA4ITGB7PYGLITGAV | |
| SCHEMBL13583833 | 0.89 | ITGB1 (0.44) | ITGB1ITGA4ITGB7PYGLITGAV | |
| SCHEMBL2330637 | 0.89 | TAS1R3 (0.58) | ITGB1ITGA4PYGLGPR139ITGAV | |
| SCHEMBL2330641 | 0.89 | TAS1R3 (0.58) | ITGB1ITGA4PYGLGPR139ITGAV | |
| SCHEMBL2330922 | 0.86 | ITGB1 (0.48) | ITGB1ITGA4ITGB7POLBPYGL | |
| SCHEMBL2328455 | 0.85 | KMT2A (0.44) | KMT2A | |
| SCHEMBL2328462 | 0.85 | KMT2A (0.44) | KMT2A | |
| SCHEMBL12985287 | 0.85 | ITGB1 (0.54) | ITGB1ITGA4ITGB7POLBGPR139 | |
| SCHEMBL2324854 | 0.84 | KDM4E (0.50) | POLBNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356979-B1 | ANTI-WRINKLE AGENTS | POLA CHEM IND INC (JP) | 2017-10-25 | — | — | EP | disclosed |
| EP-2524686-B1 | PIGMENTATION-PREVENTING OR -AMELIORATING AGENT | POLA CHEM IND INC (JP) | 2017-06-21 | — | — | EP | disclosed |
| EP-3173063-A1 | ANTI-WRINKLE AGENTS | Pola Chemical Industries Inc. (JP) | 2017-05-31 | — | — | EP | disclosed |
| US-9066914-B2 | Prophylactic or ameliorating agent for pigmentation | POLA CHEMICAL INDUSTRIES INC. (JP) | 2015-06-30 | — | — | US | disclosed |
| US-8835498-B2 | Anti-wrinkle agents | POLA CHEMICAL INDUSTRIES INC. (JP) | 2014-09-16 | — | — | US | disclosed |
| EP-2524686-A1 | PIGMENTATION-PREVENTING OR -AMELIORATING AGENT | Pola Chemical Industries Inc. (JP) | 2012-11-21 | — | — | EP | disclosed |
| US-20120282203-A1 | PROPHYLACTIC OR AMELIORATING AGENT FOR PIGMENTATION | POLA CHEMICAL INDUSTRIES INC. (JP) | 2012-11-08 | — | — | US | disclosed |
| US-20110245343-A1 | ANTI-WRINKLE AGENTS | POLA CHEMICAL INDUSTRIES INC. (JP) | 2011-10-06 | — | — | US | disclosed |
| EP-2356979-A1 | ANTI-WRINKLE AGENTS | Pola Chemical Industries Inc. (JP) | 2011-08-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120282203-A1 | PROPHYLACTIC OR AMELIORATING AGENT FOR PIGMENTATION | TYR, MC1R, NQO1 | ITGB1 1880/4885ITGA4 2227/4885ITGB7 2589/4885 |
| US-20110245343-A1 | ANTI-WRINKLE AGENTS | GLA, H1-4, H1-3 | ITGB1 3029/4885ITGA4 2166/4885ITGB7 3227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.