Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 12/20 | 0.54 |
| ▸ | ITGA4 | P13612 | 11/20 | 0.54 |
| ▸ | ITGB7 | P26010 | 11/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ITGAV | P06756 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26264262 | 0.86 | PYGL (0.60) | ITGB1ITGA4ITGB7POLBCA1 | |
| SCHEMBL26263222 | 0.86 | ITGB1 (0.56) | ITGB1ITGA4ITGB7POLBGPR139 | |
| SCHEMBL2789470 | 0.86 | ITGB1 (0.56) | ITGB1ITGA4ITGB7POLBGPR139 | |
| SCHEMBL2330851 | 0.85 | ITGB1 (0.47) | ITGB1ITGA4ITGB7POLBGPR139 | |
| SCHEMBL2330845 | 0.85 | ITGB1 (0.47) | ITGB1ITGA4ITGB7POLBGPR139 | |
| SCHEMBL16993943 | 0.84 | ITGB1 (0.67) | ITGB1ITGA4ITGB7 | |
| SCHEMBL16993942 | 0.84 | ITGB1 (0.67) | ITGB1ITGA4ITGB7 | |
| SCHEMBL28797504 | 0.83 | PYGL (0.54) | ITGB1ITGA4ITGB7POLBCA1 | |
| SCHEMBL12985034 | 0.83 | SMN1; SMN2 (0.49) | ITGB1ITGA4ITGB7POLBGPR139 | |
| SCHEMBL2330922 | 0.83 | ITGB1 (0.48) | ITGB1ITGA4ITGB7POLBGPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2514402-B1 | PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION | POLA CHEM IND INC (JP) | 2016-08-31 | — | — | EP | disclosed |
| US-9414998-B2 | Preventing or ameliorating agent for pigmentation | POLA CHEMICAL INDUSTRIES INC. (JP) | 2016-08-16 | — | — | US | disclosed |
| US-20140322150-A1 | PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION | POLA CHEMICAL INDUSTRIES INC. (JP) | 2014-10-30 | — | — | US | disclosed |
| EP-2514402-A1 | PROPHYLACTIC OR AMELIORATING AGENT FO PIGMENTATION | Pola Chemical Industries Inc. (JP) | 2012-10-24 | — | — | EP | disclosed |
| US-20120258063-A1 | PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION | POLA CHEMICAL INDUSTRIES INC. (JP) | 2012-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140322150-A1 | PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION | TYR, MC1R, MITF | ITGB1 2109/4885ITGA4 1742/4885ITGB7 2467/4885 |
| US-20120258063-A1 | PREVENTING OR AMELIORATING AGENT FOR PIGMENTATION | TYR, MC1R, MITF | ITGB1 2109/4885ITGA4 1742/4885ITGB7 2467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.