Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 11/20 | 0.60 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.60 |
| ▸ | FPR2 | P25090 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2328926 | 0.91 | HCRTR2 (0.72) | HCRTR2HCRTR1FPR2 | |
| SCHEMBL2328979 | 0.90 | FPR2 (0.64) | HCRTR2HCRTR1FPR2 | |
| SCHEMBL2324771 | 0.90 | FPR2 (0.62) | HCRTR2HCRTR1FPR2KDM4E | |
| SCHEMBL2323231 | 0.90 | FPR2 (0.68) | HCRTR2HCRTR1FPR2KDM4E | |
| SCHEMBL2327727 | 0.90 | HCRTR2 (0.58) | HCRTR2HCRTR1FPR2MAPT | |
| SCHEMBL2327561 | 0.89 | HCRTR2 (0.58) | HCRTR2HCRTR1FPR2 | |
| SCHEMBL2327045 | 0.89 | FPR2 (0.65) | HCRTR2HCRTR1FPR2 | |
| SCHEMBL2327503 | 0.88 | FPR2 (0.57) | HCRTR2HCRTR1FPR2 | |
| SCHEMBL2328204 | 0.88 | HCRTR2 (0.58) | HCRTR2HCRTR1FPR2 | |
| SCHEMBL2327838 | 0.88 | HCRTR2 (0.58) | HCRTR2HCRTR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225231-B1 | AMINOTRIAZOLE DERIVATIVES AS ALX AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-08-17 | — | — | EP | claimed |
| EP-2225231-B1 | AMINOTRIAZOLE DERIVATIVES AS ALX AGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2011-08-17 | — | — | EP | disclosed |