SCHEMBL2331132

SCHEMBL2331132

CC(=O)N[C@H](C(=O)O)C(C)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MME P08473 5/20 0.51
SMN1; SMN2 Q16637 2/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
SRC P12931 1/20 0.47
MTNR1A P48039 7/20 0.44
MTNR1B P49286 7/20 0.44
ACACB O00763 1/20 0.43
ACACA Q13085 1/20 0.43
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2329884 1.00 MME (0.51) MMESMN1; SMN2MEN1KMT2ASRC
SCHEMBL2522738 0.86 MME (0.44) MMEMEN1KMT2ASRCACACB
SCHEMBL2520019 0.84 ACACB (0.43) MMESMN1; SMN2MEN1KMT2AMTNR1A
SCHEMBL4799364 0.83 SRC (0.48) MMESMN1; SMN2MEN1KMT2ASRC
SCHEMBL762079 0.83 SRC (0.48) MMESMN1; SMN2MEN1KMT2ASRC
SCHEMBL14278787 0.83 SRC (0.48) MMESMN1; SMN2MEN1KMT2ASRC
SCHEMBL9462002 0.82 SLC1A2 (0.60) MMESMN1; SMN2KMT2ALMNAHPGD
SCHEMBL8602939 0.82 MME (0.49) MMESMN1; SMN2KMT2ALMNAGAA
SCHEMBL9461816 0.82 SLC1A2 (0.60) MMESMN1; SMN2KMT2ALMNAHPGD
SCHEMBL9461814 0.82 SLC1A2 (0.60) MMESMN1; SMN2KMT2ALMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9025275-A None JP disclosed
EP-2534161-A1 ENANTIOMERICALLY ENRICHED AMINODIPHOSPHINES AS LIGANDS FOR THE PREPARATION OF CATALYSTS FOR ASYMMETRIC SYNTHESIS Enantia, S.L. (ES) 2012-12-19 EP disclosed
US-20120309997-A1 Enantiomerically Enriched Aminodiphosphines as Ligands for the Preparation of Catalysts for Asymmetric Synthesis ENANTIA, S.L. (ES) 2012-12-06 US disclosed
WO-2011098160-A1 ENANTIOMERICALLY ENRICHED AMINODIPHOSPHINES AS LIGANDS FOR THE PREPARATION OF CATALYSTS FOR ASYMMETRIC SYNTHESIS ENANTIA, S.L. (ES) 2011-08-18 WO disclosed
JP-H0925275-A AMINO ACID ESTER DERIVATIVE AND HERBICIDE CONTAINING THE DERIVATIVE OTSUKA CHEM CO LTD 1997-01-28 JP disclosed
EP-0226304-B1 COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC SANKYO COMPANY LIMITED (JP) 1991-08-28 EP disclosed
US-4757066-A Reduces renal toxicity SANKYO COMPANY LIMITED (JP) 1988-07-12 US disclosed
EP-0226304-A1 Composition containing a penem or carbapenem antibiotic SANKYO COMPANY LIMITED (JP) 1987-06-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120309997-A1 Enantiomerically Enriched Aminodiphosphines as Ligands for the Preparation of Catalysts for Asymmetric Synthesis PHOSPHO1, AASDHPPT, AGPS MME 1666/4885SMN1; SMN2 4541/4885MEN1 1946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.