Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.57 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25353746 | 0.89 | GPR119 (0.44) | GPR119 | |
| SCHEMBL2778000 | 0.89 | GPR119 (0.59) | GPR119HRH3CHEK2 | |
| SCHEMBL28671495 | 0.86 | GPR119 (0.56) | GPR119 | |
| SCHEMBL1103942 | 0.85 | GPR119 (0.57) | GPR119CHEK2 | |
| SCHEMBL20590907 | 0.84 | GPR119 (0.58) | GPR119CHEK2 | |
| SCHEMBL19504087 | 0.83 | GPR119 (0.54) | GPR119NPBWR1MCHR1CHEK2 | |
| SCHEMBL15536268 | 0.83 | GPR119 (0.50) | GPR119NPBWR1MCHR1 | |
| SCHEMBL29947210 | 0.83 | GPR119 (0.50) | GPR119NPBWR1MCHR1 | |
| SCHEMBL2775170 | 0.83 | GPR119 (0.54) | GPR119CHEK2 | |
| SCHEMBL22266058 | 0.82 | GPR119 (0.59) | GPR119NPBWR1MCHR1HRH3CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210122763-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN-CILAG S.A. (ES) | 2021-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210122763-A1 | OGA INHIBITOR COMPOUNDS | OGA, OGT, GRN | GPR119 1166/4885NPBWR1 4748/4885MCHR1 4744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.