Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 17/20 | 0.68 |
| ▸ | BCHE | P06276 | 7/20 | 0.68 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6198882 | 0.95 | ACHE (0.73) | ACHEBCHE | |
| SCHEMBL8924503 | 0.91 | ACHE (0.73) | ACHEBCHE | |
| Maleic Acid SCHEMBL3926936 | 0.90 | ACHE (0.77) | ACHEBCHENPY2R | |
| SCHEMBL16062330 | 0.86 | ACHE (0.61) | ACHEBCHEFAAH | |
| SCHEMBL2402320 | 0.85 | ACHE (0.90) | ACHEBCHE | |
| Icopezil SCHEMBL194482 | 0.81 | ACHE (1.00) | ACHEBCHE | |
| SCHEMBL4512593 | 0.79 | ACHE (1.00) | ACHEBCHE | |
| Icopezil SCHEMBL3339253 | 0.78 | ACHE (1.00) | ACHEBCHE | |
| Icopezil SCHEMBL2231222 | 0.78 | ACHE (1.00) | ACHEBCHE | |
| SCHEMBL3406040 | 0.77 | ACHE (0.50) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968220-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | Agenebio, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014144801-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | AGENEBIO INC. (US) | 2014-09-18 | — | — | WO | disclosed |
| EP-2533645-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | The Johns Hopkins University (US) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011100373-A1 | METHODS AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-08-18 | — | — | WO | disclosed |