Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL344924 | 0.91 | SYK (0.35) | IRAK4 | |
| SCHEMBL2327815 | 0.75 | CHRM1 (0.36) | — | |
| SCHEMBL2324598 | 0.69 | CHRM1 (0.35) | — | |
| SCHEMBL2331284 | 0.69 | ADRB1 (0.40) | — | |
| SCHEMBL345079 | 0.67 | MAPT (0.36) | — | |
| SCHEMBL2329304 | 0.66 | TACR1 (0.30) | — | |
| SCHEMBL346214 | 0.64 | SLC6A2 (0.37) | — | |
| Trifluoroacetic Acid SCHEMBL345531 | 0.61 | KMT2A (0.34) | — | |
| SCHEMBL344922 | 0.61 | ADRB1 (0.38) | — | |
| SCHEMBL1728758 | 0.60 | ADRB1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356108-B1 | CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2014-10-15 | — | — | EP | disclosed |
| EP-2356108-A1 | CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010055267-A1 | CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-05-20 | — | — | WO | disclosed |