Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 4/20 | 0.38 |
| ▸ | AKT1 | P31749 | 7/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | IDH2 | P48735 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1729058 | 0.79 | F11 (0.45) | SMYD3AKT1CDK2 | |
| SCHEMBL2329433 | 0.75 | AKT1 (0.41) | SMYD3AKT1CDK2MAPK1 | |
| SCHEMBL27600626 | 0.72 | AKT1 (0.41) | SMYD3AKT1CDK2 | |
| SCHEMBL2333984 | 0.71 | AKT1 (0.45) | SMYD3AKT1CDK2KCNH2 | |
| SCHEMBL6066725 | 0.70 | AAK1 (0.44) | SMYD3AKT1CDK2 | |
| SCHEMBL3701313 | 0.69 | AKT1 (0.43) | SMYD3AKT1CDK2 | |
| SCHEMBL4071612 | 0.69 | SMYD3 (0.60) | SMYD3AKT1CDK2 | |
| SCHEMBL1729018 | 0.68 | SMYD3 (0.43) | SMYD3AKT1CDK2 | |
| SCHEMBL1729837 | 0.68 | SMYD3 (0.42) | SMYD3AKT1CDK2 | |
| SCHEMBL1728731 | 0.67 | SMYD3 (0.41) | SMYD3AKT1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633735-B1 | DERIVATIVES OF PIPERIDINYL- AND PIPERAZINYL-ALKYL CARBAMATES, PREPARATION METHODS THEREOF AND APPLICATION OF SAME IN THERAPEUTICS | SANOFI SA (FR) | 2011-11-30 | — | — | EP | claimed |