Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 15/20 | 0.67 |
| ▸ | METTL3 | Q86U44 | 9/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29772267 | 0.85 | PRMT5 (0.57) | PRMT5METTL3FLT3WDR77 | |
| SCHEMBL23273740 | 0.85 | PRMT5 (0.57) | PRMT5METTL3FLT3WDR77 | |
| SCHEMBL29772292 | 0.80 | PRMT5 (1.00) | PRMT5METTL3FLT3WDR77 | |
| SCHEMBL23313047 | 0.80 | PRMT5 (1.00) | PRMT5METTL3FLT3WDR77 | |
| SCHEMBL25015483 | 0.72 | PRMT5 (0.44) | PRMT5METTL3FLT3WDR77 | |
| SCHEMBL29772287 | 0.72 | PRMT5 (0.44) | PRMT5METTL3FLT3WDR77 | |
| SCHEMBL23313081 | 0.67 | PRMT5 (1.00) | PRMT5METTL3 | |
| SCHEMBL25017608 | 0.66 | METTL3 (1.00) | PRMT5METTL3 | |
| SCHEMBL23313120 | 0.66 | METTL3 (1.00) | PRMT5METTL3 | |
| SCHEMBL23313944 | 0.64 | PRMT5 (0.90) | PRMT5METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021079196-A9 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2022-07-14 | — | — | WO | disclosed |
| WO-2021079196-A2 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2021-04-29 | — | — | WO | disclosed |