Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 14/20 | 1.00 |
| ▸ | METTL3 | Q86U44 | 11/20 | 0.71 |
| ▸ | FLT3 | P36888 | 1/20 | 0.63 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23313047 | 1.00 | PRMT5 (1.00) | PRMT5METTL3FLT3WDR77 | |
| SCHEMBL23313120 | 0.83 | METTL3 (1.00) | PRMT5METTL3 | |
| SCHEMBL23313081 | 0.83 | PRMT5 (1.00) | PRMT5METTL3 | |
| SCHEMBL25017608 | 0.82 | METTL3 (1.00) | PRMT5METTL3 | |
| SCHEMBL23313045 | 0.80 | PRMT5 (0.67) | PRMT5METTL3FLT3WDR77 | |
| SCHEMBL23313944 | 0.78 | PRMT5 (0.90) | PRMT5METTL3 | |
| SCHEMBL23313941 | 0.78 | PRMT5 (1.00) | PRMT5METTL3 | |
| SCHEMBL24314152 | 0.77 | PRMT5 (1.00) | PRMT5METTL3FLT3WDR77 | |
| SCHEMBL25017613 | 0.76 | METTL3 (1.00) | PRMT5METTL3 | |
| SCHEMBL23313216 | 0.76 | PRMT5 (1.00) | PRMT5METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4048674-A2 | METTL3 MODULATORS | Accent Therapeutics, Inc. (US) | 2022-08-31 | — | — | EP | disclosed |
| WO-2021079196-A9 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2022-07-14 | — | — | WO | disclosed |