Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 14/20 | 0.73 |
| ▸ | METTL3 | Q86U44 | 13/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23313214 | 0.91 | METTL3 (0.72) | PRMT5METTL3 | |
| SCHEMBL25015913 | 0.84 | PRMT5 (1.00) | PRMT5METTL3 | |
| SCHEMBL25015669 | 0.83 | PRMT5 (1.00) | PRMT5METTL3 | |
| SCHEMBL18572075 | 0.81 | PRMT5 (0.81) | PRMT5METTL3 | |
| SCHEMBL22002187 | 0.80 | METTL3 (0.84) | PRMT5METTL3 | |
| SCHEMBL25015663 | 0.78 | PRMT5 (1.00) | PRMT5METTL3 | |
| SCHEMBL23313083 | 0.77 | PRMT5 (1.00) | PRMT5METTL3 | |
| SCHEMBL25016895 | 0.76 | METTL3 (1.00) | PRMT5METTL3 | |
| SCHEMBL17816346 | 0.76 | ADK (0.61) | — | |
| SCHEMBL17816351 | 0.76 | ADK (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021079196-A9 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2022-07-14 | — | — | WO | disclosed |
| WO-2021079196-A2 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2021-04-29 | — | — | WO | disclosed |