Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | MGLL | Q99685 | 1/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | IDE | P14735 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18804483 | 0.82 | MEN1 (0.72) | MEN1KMT2APOLBATMMGLL | |
| SCHEMBL14722021 | 0.82 | MEN1 (0.52) | MEN1KMT2APOLBATMALDH1A1 | |
| SCHEMBL3119437 | 0.81 | ATM (0.55) | MEN1KMT2APOLBATMMGLL | |
| SCHEMBL15978112 | 0.79 | MEN1 (0.53) | MEN1KMT2APOLBATMMGLL | |
| SCHEMBL9923584 | 0.78 | MEN1 (0.57) | MEN1KMT2APOLBATMMGLL | |
| SCHEMBL17236309 | 0.78 | MGLL (0.56) | MEN1KMT2APOLBATMMGLL | |
| SCHEMBL10031597 | 0.78 | MEN1 (0.57) | MEN1KMT2APOLBATMMGLL | |
| SCHEMBL12858556 | 0.76 | ELANE (0.60) | MEN1KMT2AMGLLCACNA1BAPBA1 | |
| SCHEMBL26590830 | 0.76 | MEN1 (0.59) | MEN1KMT2APOLBATMMGLL | |
| SCHEMBL905973 | 0.76 | ATM (0.59) | MEN1KMT2APOLBATMCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210187005-A1 | PHARMACEUTICAL COMPOSITION | KAWASAKI INSTITUTE OF INDUSTRIAL PROMOTION (JP) | 2021-06-24 | — | — | US | disclosed |
| US-10993960-B1 | Pharmaceutical composition | KAWASAKI INSTITUTE OF INDUSTRIAL PROMOTION (JP) | 2021-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210187005-A1 | PHARMACEUTICAL COMPOSITION | ABCB11, ABCB1, ABCG2 | MEN1 1597/4885KMT2A 4508/4885POLB 171/4885 |
| US-10993960-B1 | Pharmaceutical composition | ABCB11, ABCB1, ABCG2 | MEN1 1597/4885KMT2A 4508/4885POLB 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.