Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 2/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | CPA1 | P15085 | 1/20 | 0.35 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GNPAT | O15228 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17282588 | 0.84 | ALDH1A1 (0.45) | ALDH1A1MAPTFAAHSMN1; SMN2SLC6A5 | |
| SCHEMBL594483 | 0.80 | — | — | |
| SCHEMBL594482 | 0.80 | — | — | |
| SCHEMBL2792653 | 0.80 | — | — | |
| SCHEMBL18681012 | 0.79 | ALDH1A1 (0.42) | ALDH1A1MAPTFAAHSMN1; SMN2SLC6A5 | |
| Hydrazine SCHEMBL27924753 | 0.78 | RAB9A (0.41) | ALDH1A1MAPTSMN1; SMN2KDM4ETSHR | |
| SCHEMBL28262449 | 0.78 | MME (0.41) | ALDH1A1MAPTSMN1; SMN2KDM4ETSHR | |
| SCHEMBL4572566 | 0.77 | ALDH1A1 (0.51) | ALDH1A1MAPTFAAHSMN1; SMN2SLC6A5 | |
| SCHEMBL2805775 | 0.77 | ALDH1A1 (0.51) | ALDH1A1MAPTFAAHSMN1; SMN2SLC6A5 | |
| SCHEMBL434917 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MAPTFAAHSMN1; SMN2SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3145944-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2021-05-05 | — | — | EP | disclosed |