Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ECE1 | P42892 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19861713 | 0.84 | TSHR (0.37) | TSHRPRKCAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL27546947 | 0.77 | TSHR (0.41) | TSHRPRKCAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9160535 | 0.74 | TSHR (0.38) | TSHRPRKCAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL9160545 | 0.74 | TSHR (0.38) | TSHRPRKCAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL128660 | 0.74 | TSHR (0.48) | TSHRPRKCAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL13711119 | 0.73 | CYP2D6 (0.41) | GAA | |
| SCHEMBL13710929 | 0.73 | CYP2D6 (0.41) | GAA | |
| SCHEMBL992852 | 0.72 | ECE1 (0.44) | ALDH1A1ECE1 | |
| SCHEMBL992850 | 0.72 | ECE1 (0.44) | ALDH1A1ECE1 | |
| SCHEMBL24915343 | 0.72 | ECE1 (0.44) | ALDH1A1ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3145944-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2021-05-05 | — | — | EP | disclosed |