Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PRKCA | P17252 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160545 | 1.00 | TSHR (0.38) | TSHRALDH1A1PRKCATDP1L3MBTL1 | |
| SCHEMBL21952335 | 0.78 | DPP4 (0.37) | TSHRALDH1A1PRKCATDP1L3MBTL1 | |
| SCHEMBL21952760 | 0.78 | DPP4 (0.37) | TSHRALDH1A1PRKCATDP1L3MBTL1 | |
| SCHEMBL22621222 | 0.78 | L3MBTL1 (0.34) | TSHRTDP1L3MBTL1SMN1; SMN2POLB | |
| SCHEMBL128660 | 0.77 | TSHR (0.48) | TSHRALDH1A1PRKCATDP1L3MBTL1 | |
| SCHEMBL8583393 | 0.76 | GAA (0.50) | TSHRALDH1A1TDP1L3MBTL1POLB | |
| SCHEMBL8583399 | 0.76 | GAA (0.50) | TSHRALDH1A1TDP1L3MBTL1POLB | |
| SCHEMBL19861713 | 0.76 | TSHR (0.37) | TSHRALDH1A1PRKCATDP1L3MBTL1 | |
| SCHEMBL15491409 | 0.75 | TSHR (0.43) | TSHRALDH1A1PRKCATDP1L3MBTL1 | |
| SCHEMBL2458412 | 0.75 | TSHR (0.43) | TSHRALDH1A1PRKCATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405987-A | N-hydroxyaspartic acid derivatives; chemical intermediates | HOECHST CELANESE CORPORATION (US) | 1995-04-11 | — | — | US | claimed |
| EP-0511446-A2 | Process for preparing pyridinecarboxylic acid derivatives | HOECHST CELANESE CORPORATION (US) | 1992-11-04 | — | — | EP | claimed |
| CN-1058205-A | The method for preparing pyridine and quinoline | HOECHST CELANESE CORP (US) | 1992-01-29 | — | — | CN | claimed |
| EP-0452094-A2 | A method of the preparation of N-hydroxy aspartic acid derivate | HOECHST CELANESE CORPORATION (US) | 1991-10-16 | — | — | EP | claimed |